Open access peer-reviewed Edited Volume

The Metabolic Role of Peroxisome in Health and Disease

Hasan İla

Cukurova University

Prof. Dr. Hasan Basri İla is a researcher in cytology and cytogenetics, experienced in genotoxicity/cytotoxicity, with one registered patent. He is also a member of the Turkish Biologists Association.

Covering

Peroxisome PPAR Cell Signaling Pharmacology Oxidative Stress Inflammatory Response Antioxidant Defense Apoptosis Cancer Neurodegenerative Disease Chronic Disease Gene Expression

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About the book

The cell, which has been optimized for current conditions in the evolution process, has developed many mechanisms to adapt to changing environmental conditions. This adaptation mechanism in the cell is called homeostasis. Every cell needs the support of cellular components to maintain its vitality in a balanced way. Peroxisomes play a leading role in the fight against oxidative stress, which has recently become more and more popular and is one of the most vital compartments in the cell. Catalase, one of the oldest and most well-known actors of antioxidant defense, is located in the peroxisome. As it is known, catalase is an important enzyme that degrades hydrogen peroxide (H2O2) molecules into H2O and O2. If catalase and other components fail in their functions, H2O2 in the cell attacks all molecular forms. As a result, cellular homeostasis will be impaired and, in some cases, apoptosis will be inevitable. Even if apoptosis does not occur, DNA molecules are damaged excessively by oxidized molecules (such as H2O2), and mutations that can cause cancer to occur. Considering the current projection, it is very important to understand the peroxisome and its structural elements.

This book is intended to increase the depth of knowledge about peroxisome and to challenge the old and templated perspectives towards related phenomena.

Publishing process

Book initiated and editor appointed

Date completed: November 11th 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: December 9th 2021

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: February 7th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 28th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: June 27th 2022

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About the editor

Hasan İla

Cukurova University

Prof. Dr. Hasan Basri İla received his Ph.D. from the Biology Department of Çukurova University, Institute of Sciences and Letters. During his doctoral study, Dr. İla investigated the effects of a commonly used antibiotic on chromosome aberration and micronucleus formation by in vivo tests. He actively took responsibility for 19 national projects as a researcher and/or project leader, and has numerous poster and/or oral scientific presentations in several international conferences. He has also actively been giving lectures on biology, cytology, genetics, evolution, organelle genetics, and cancer genetics. Dr. İla has several publications in internationally indexed journals (SCI, SCI-E), and his articles have been cited 636 times.

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