Open access peer-reviewed Edited Volume

Reactive Oxygen Species (ROS) in Living Cells


Oxygen represents only 20% of the Earth's atmosphere, yet it is vital for the survival of aerobic organisms. There is a dark part of the use of oxygen that consists in generating reactive species that are potentially harmful to living organisms. Moreover, reactive oxygen species can combine with nitrogen derivatives and generate many other reactive species. Thus, living organisms are continuously assaulted by reactive species from external or internal sources. However, the real danger comes in the case of high concentrations and prolonged exposure to these species. This book presents an image of the mechanisms of action of reactive species and emphasizes their involvement in diseases. Inflammation and cancer are examined to determine when and how reactive species turn the evolution of a benign process to a malignant one. Some answers may come from recent studies indicating that reactive species are responsible for epigenetic changes.

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Reactive Oxygen Species (ROS) in Living CellsEdited by Filip Cristiana

Published: May 23rd 2018

DOI: 10.5772/intechopen.69697

ISBN: 978-1-78923-135-9

Print ISBN: 978-1-78923-134-2

eBook (PDF) ISBN: 978-1-83881-409-0

Copyright year: 2018

Books open for chapter submissions

12494 Total Chapter Downloads

33 Crossref Citations

13 Web of Science Citations

65 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: The Biology of Reactive Species

By Filip Cristiana


Open access peer-reviewed

2. Reactive Oxygen Species: The Good and the Bad

By Roma Patel, Lindsey Rinker, Joanna Peng and William M. Chilian


Open access peer-reviewed

3. Role of Antioxidant Phytochemicals in Prevention, Formation and Treatment of Cancer

By Abdurrahim Kocyigit, Eray Metin Guler and Murat Dikilitas


Open access peer-reviewed

4. Reactive Oxygen Species and Bone Fragility

By Nina Filip, Elena Cojocaru, Alexandru Filip, Bogdan Veliceasa and Ovidiu Alexa


Open access peer-reviewed

5. Reactive Oxygen Species in Skin Repair, Regeneration, Aging, and Inflammation

By Hui Xu, Yun-Wen Zheng, Qi Liu, Li-Ping Liu, Feng-Lin Luo, Hu-Chen Zhou, Hiroko Isoda, Nobuhiro Ohkohchi and Yu-Mei Li


Open access peer-reviewed

6. Reactive Oxygen Species and Sperm Cells

By Teppei Takeshima, Shinnosuke Kuroda and Yasushi Yumura


Open access peer-reviewed

7. Reactive Oxygen Species at High Altitude (Hypobaric Hypoxia) on the Cardiovascular System

By Patricia Siques, Julio Brito and Eduardo Pena


Open access peer-reviewed

8. Oxidative Stress in Urolithiasis

By Chanchai Boonla


Open access peer-reviewed

9. Biomolecules Oxidation by Hydrogen Peroxide and Singlet Oxygen

By Kazutaka Hirakawa


Open access peer-reviewed

10. Soil Remediation Assessment by Detection of Reactive Oxygen Species in Lizard Testis: An Electron Spin Resonance (ESR) Approach

By Giulia Guerriero, Gerardino D’Errico, Anna De Maio, Anna Rita Bianchi, Oladokun Sulaiman Olanrewaju and Gaetano Ciarcia


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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