Margarete Dulce Bagatini

Universidade Federal da Fronteira Sul

Dr. Margarete Dulce Bagatini is an associate professor at the Federal University of Fronteira Sul (UFFS), Brazil. She has a degree in Pharmacy and a Ph.D. in Biological Sciences (Toxicological Biochemistry). She is a member of the UFFS research advisory committee and the Biovitta Research Institute. She is currently the leader of the Biological and Clinical Studies in Human Pathologies research group. She is also a professor of postgraduate programs in Biomedical Sciences and Science and Food Technology at UFFS and the postgraduate program in Biochemistry at the Federal University of Santa Catarina (UFSC), Brazil. She has experience in pharmacy and clinical analysis, including in oxidative stress, the purinergic system, and human pathologies. Dr. Bagatini is a reviewer of several international journals and books.

Margarete Dulce Bagatini

2books edited

3chapters authored

Latest work with IntechOpen by Margarete Dulce Bagatini

Characterized as a common signaling pathway between cells, the purinergic system is capable of modulating physiological and biochemical processes. Composed of signaling molecules, regulatory enzymes, and specific receptors, this organization can modulate several basal pathways of the organism. It is understood that purinergic signaling is present in all aspects of immunity and inflammation and studies show that extracellular ATP and its adenosine metabolite are the main mediators of response. These occur since most immune cells express P2 and P1 receptors, which are sensitive to the ATP and adenosine molecules, respectively. This book describes the purinergic system and its correlation with the health and disease process.

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