Margarete Dulce Bagatini

Universidade Federal da Fronteira Sul

Dr. Margarete Dulce Bagatini is an associate professor at the Federal University of Fronteira Sul/Brazil. She has a degree in Pharmacy and a PhD in Biological Sciences: Toxicological Biochemistry. She is a member of the UFFS Research Advisory Committee and a member of the Biovitta Research Institute. She is currently: the leader of the research group: Biological and Clinical Studies in Human Pathologies, professor of postgraduate program in Biochemistry at UFSC and postgraduate program in Science and Food Technology at UFFS. She has experience in the area of pharmacy and clinical analysis, acting mainly on the following topics: oxidative stress, the purinergic system and human pathologies, being a reviewer of several international journals and books.

1books edited

2chapters authored

Latest work with IntechOpen by Margarete Dulce Bagatini

The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.

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