Open access peer-reviewed Edited Volume


Edited by Margarita Guenova

Laboratory of Haematopathology and Immunology, National Specialized Hospital for Active Treatment of Haematological Diseases, Sofia, Bulgaria


Leukemias are a group of heterogeneous neoplastic disorders, that differ significantly in terms of morhological, immunophenotypic, cytogenetic and molecular features of malignant cells. These specific features reflect the differences in the spectrum of underlying biological alterations involved in malignant transformation, and/or variations in the level of hematopoietic stem cells hierarchy where the transforming events occur. The continuous and rather extensive influx of new information regarding the pathogenesis and treatment of leukemias requires a frequent updating of this topic. The primary objective of this book is to provide the specialists involved in the diagnosis and management of acute and chronic leukemias with a comprehensive and concise information on some important theoretical and practical issues of the biology and clinical presentation, the diagnosis, treatment and follow up of patients with leukemias.

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LeukemiaEdited by Margarita Guenova

Published: May 15th 2013

DOI: 10.5772/45914

ISBN: 978-953-51-1127-6

eBook (PDF) ISBN: 978-953-51-7150-8

Copyright year: 2013

Books open for chapter submissions

24777 Total Chapter Downloads

8 Crossref Citations

11 Web of Science Citations

19 Dimensions Citations


Open access peer-reviewed

1. Genetics of Acute Lymphoblastic Leukemia

By Ruth Maribel Forero, María Hernández and Jesús María Hernández- Rivas


Open access peer-reviewed

2. Acute Lymphoblastic Leukemia in Children

By Jelena Roganovic


Open access peer-reviewed

3. Acute Leukemia Clinical Presentation

By Gamal Abdul Hamid


Open access peer-reviewed

4. Therapy-Related Acute Myeloid Leukemias

By Margarita Guenova, Gueorgui Balatzenko and Georgi Mihaylov


Open access peer-reviewed

5. Treatment of Myelodysplastic Syndrome and Acute Myeloid Leukemia by Immunomodulatory and Epigenetic Drugs

By Ota Fuchs


Open access peer-reviewed

6. Minimal Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia

By W. Zeijlemaker and G.J. Schuurhuis


Open access peer-reviewed

7. Modern Therapy of Chronic Myeloid Leukemia

By M.M. Zaharieva, G. Amudov, S.M. Konstantinov and M. L. Guenova


Edited Volume and chapters are indexed in

  • Worldcat
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  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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