Open access peer-reviewed Edited Volume

Applications of RNA-Seq in Biology and Medicine

Edited by Irina Vlasova-St. Louis

Nevada State Public Health Laboratory

This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation.

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Applications of RNA-Seq in Biology and MedicineEdited by Irina Vlasova-St. Louis

Published: October 13th 2021

DOI: 10.5772/intechopen.91555

ISBN: 978-1-83962-815-3

Print ISBN: 978-1-83962-686-9

eBook (PDF) ISBN: 978-1-83962-816-0

Copyright year: 2021

Books open for chapter submissions

319 Total Chapter Downloads


Open access peer-reviewed

1. Introductory Chapter: Applications of RNA-Seq Diagnostics in Biology and Medicine

By Irina Vlasova-St. Louis


Open access peer-reviewed

2. RNA Sequencing in Potentially Malignant Disorders

By Ramya Ramadoss, Rajkumar Krishnan, Lekshmy Jayan and Priyadharini Shankaran


Open access peer-reviewed

3. Insights into Oropharyngeal Microbiota, Biofilms and Associated Diseases from Metagenomics and Transcriptomic Approaches

By Richa Priyadarshini, Karthik Krishnan and Rashmi Niranjan


Open access peer-reviewed

4. Assessing Host-Pathogen Interaction Networks via RNA-Seq Profiling: A Systems Biology Approach

By Sudhesh Dev Sareshma and Bhassu Subha


Open access peer-reviewed

5. Diagnostic Applications for RNA-Seq Technology and Transcriptome Analyses in Human Diseases Caused by RNA Viruses

By Irina Vlasova-St. Louis, Andrew Gorzalski and Mark Pandori


Open access peer-reviewed

6. Recent Applications of RNA Sequencing in Food and Agriculture

By Venkateswara R. Sripathi, Varsha C. Anche, Zachary B. Gossett and Lloyd T. Walker


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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