Open access peer-reviewed Edited Volume

Glutathione in Health and Disease

Edited by Pınar Erkekoglu

Hacettepe University


Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia. This book is mainly focused on GSH in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.

Read more >Order hardcopy
Glutathione in Health and DiseaseEdited by Pınar Erkekoglu

Published: October 31st 2018

DOI: 10.5772/intechopen.70965

ISBN: 978-1-78984-276-0

Print ISBN: 978-1-78984-275-3

eBook (PDF) ISBN: 978-1-83881-493-9

Copyright year: 2018

Books open for chapter submissions

5862 Total Chapter Downloads

6 Crossref Citations

3 Web of Science Citations

11 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: A General Overview of Glutathione, Glutathione Transport, and Glutathione Applications

By Pinar Erkekoglu


Open access peer-reviewed

2. The Life Evolution on the Sulfur Cycle: From Ancient Elemental Sulfur Reduction and Sulfide Oxidation to the Contemporary Thiol-Redox Challenges

By Roberto C. Burini, Hugo T. Kano and Yong-Ming Yu


Open access peer-reviewed

3. The Important Functions of GSH-Dependent Enzyme Glutaredoxin 2 (Grx2)

By Christy Xavier, Xiaobin Liu, Yang Liu and Hongli Wu


Open access peer-reviewed

4. Impact of Oxidative Changes and Possible Effects of Genetics Polymorphisms of Glutathione S-Transferase in Diabetics Patients with Complications

By Laura Raniere Borges dos Anjos, Ana Cristina Silva Rebelo, Gustavo Rodrigues Pedrino, Rodrigo da Silva Santos and Angela Adamski da Silva Reis


Open access peer-reviewed

5. The Role of Glutathione in Viral Diseases of the Central Nervous System

By Juliana Echevarria Lima


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£100

Order now

Residents of European Union countries need to add a Book Value-Added Tax Rate based on their country of residence. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase