Irina Vlasova-St. Louis

Nevada State Public Health Laboratory

Dr. Vlasova-St. Louis earned her MD and Ph.D. from Ural State Medical Academy, Russia. She completed her postdoctoral training at the University of Minnesota, USA, and a fellowship sponsored by the Lymphoma Research Foundation. She served as an assistant professor at the Department of Medicine, University of Minnesota. Dr. Vlasova-St. Louis has expertise in several biological disciplines including infectious diseases, immunology, and bioinformatics. By integrating state-of-the-art techniques such as next-generation sequencing, she made numerous biomedical discoveries studying normal and pathological conditions at the molecular, cellular, and organismal levels. Currently, Dr. St. Louis is a COVID-19 Associate, sponsored by the Association of Public Health Laboratories and the Center for Disease Control and Prevention. She leads the molecular surveillance program of novel SARS-CoV-2 variants.

1books edited

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Latest work with IntechOpen by Irina Vlasova-St. Louis

This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation.

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