Irina Vlasova-St. Louis

Johns Hopkins University United States of America

Dr. Irina Vlasova-St. Louis obtained her MD and Ph.D. from Ural State Medical Academy, Russia. She completed her postdoctoral training at the University of Minnesota, USA, and a laboratory fellowship sponsored by the Lymphoma Research Foundation. She served as an assistant professor at the University of Minnesota, Department of Medicine, providing expertise in several biological disciplines including infectious diseases, immunology, genomics, and bioinformatics. During the COVID-19 pandemic, Dr. Vlasova-St. Louis led genomic surveillance of circulating SARS-CoV-2 variants of concern in Nevada, USA. Currently, she is a genomics specialist at the Newborn Screening Department, Texas Department of State Health Services, USA. She is sponsored by federal grants from the Association of Public Health Laboratories and Centers for Disease Control and Prevention. She is a part of the Johns Hopkins University Advanced Academic Program: Individualized Genomics and Health.

Irina Vlasova-St. Louis

2books edited

5chapters authored

Latest work with IntechOpen by Irina Vlasova-St. Louis

RNA therapies evolved as economical and widely applicable individualized treatment solutions. Novel RNA-based therapeutic vaccines (e.g., against SARS-CoV-2 infection) have been proven to be safe and effective, and many of them are approved by the United States Food and Drug Administration (FDA). This book presents distinct classes of RNA therapeutics, ranging from single-stranded antisense oligonucleotides (ASOs) and subclasses of RNA interferences (miRNAs and other RNAi) to in vitro transcribed and in vivo translated mRNAs drugs and RNA vaccines. The book also discusses some of the challenges in RNA drug engineering, delivery, and specificity, as well as highlights the improvement of pharmacological effectiveness in a wide range of diseases.

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