Open access peer-reviewed Edited Volume

Calcium and Signal Transduction

Edited by John N. Buchholz

Loma Linda University, United States of America


Erik J. Behringer

University of Missouri, United States of America

Since the development of microelectronic clamping methodology and fluorescent indicators for direct measurement of dynamic intracellular calcium transients, our understanding of biological signal transduction has progressed dramatically since the 1980s. Calcium is a universal signal in biology that modulates gene expression, transmitter and hormone release, muscular movement, and even "programmed" cell death. This book represents a compilation of chapters from a diverse set of expert biologists throughout the world who have conducted research in the general area of calcium signaling in organisms ranging from bacteria to humans. In accord with priorities of resolving human disease, the reader will also benefit from learning calcium's role in cellular signaling pathology relating to acute or chronic conditions such as vomiting, sepsis, obesity, hypertension, and cancer.

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Calcium and Signal TransductionEdited by John N. Buchholz

Published: October 24th 2018

DOI: 10.5772/intechopen.74489

ISBN: 978-1-78984-250-0

Print ISBN: 978-1-78984-249-4

eBook (PDF) ISBN: 978-1-83881-797-8

Copyright year: 2018

Books open for chapter submissions

7131 Total Chapter Downloads

11 Crossref Citations

5 Web of Science Citations

16 Dimensions Citations


Open access peer-reviewed

1. Regulation of Calcium Signaling by STIM1 and ORAI1

By Francisco Javier Martin-Romero, Carlos Pascual-Caro, Aida Lopez- Guerrero, Noelia Espinosa-Bermejo and Eulalia Pozo-Guisado


Open access peer-reviewed

2. Calcium and Cell Response to Heavy Metals: Can Yeast Provide an Answer?

By Ileana Cornelia Farcasanu, Claudia Valentina Popa and Lavinia Liliana Ruta


Open access peer-reviewed

3. The Endothelium: The Vascular Information Exchange

By Ran Wei, Stephanie E. Lunn, Stephen L. Gust, Paul M. Kerr and Frances Plane


Open access peer-reviewed

4. Mineralocorticoid Receptor in Calcium Handling of Vascular Smooth Muscle Cells

By Rogelio Salazar-Enciso, Nohemi A. Camacho-Concha, Thassio R. Mesquita, Débora Falcón, Jean-Pierre Benitah, Ana M. Gómez and Angélica Rueda


Open access peer-reviewed

5. Calcium Signaling in Prokaryotes

By Delfina C. Domínguez


Open access peer-reviewed

6. Role of Calcium in Vomiting

By Weixia Zhong and Nissar A. Darmani


Open access peer-reviewed

7. Calcium Signaling Initiated by Agonists in Mesenchymal Stromal Cells from the Human Adipose Tissue

By Polina D. Kotova, Olga A. Rogachevskaja, Marina F. Bystrova, Ekaterina N. Kochkina, Denis S. Ivashin and Stanislav S. Kolesnikov


Open access peer-reviewed

8. Alterations in Calcium Signaling Pathways in Breast Cancer

By Adrian Dumitru, Daniela Oana Toader, Sanda Maria Cretoiu, Dragos Cretoiu, Nicolae Suciu and Beatrice Mihaela Radu


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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