Open access peer-reviewed Edited Volume

Ion Channels in Health and Sickness

Edited by Kaneez Fatima Shad

University of Technology Sydney

Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins.

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Ion Channels in Health and SicknessEdited by Kaneez Fatima Shad

Published: October 10th 2018

DOI: 10.5772/intechopen.72025

ISBN: 978-1-78984-228-9

Print ISBN: 978-1-78984-227-2

eBook (PDF) ISBN: 978-1-83881-642-1

Copyright year: 2018

Books open for chapter submissions

10906 Total Chapter Downloads

8 Crossref Citations

8 Web of Science Citations

16 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Ion Channels

By Kaneez Fatima Shad, Saad Salman, Saifullah Afridi, Muniba Tariq and Sajid Asghar


Open access peer-reviewed

2. Voltage-Gated Sodium Channels in Drug Discovery

By Tianbo Li and Jun Chen


Open access peer-reviewed

3. Voltage-Gated Sodium Channel Drug Discovery Technologies and Challenges

By Tianbo Li and Jun Chen


Open access peer-reviewed

4. Genetic Defects of Voltage-Gated Sodium Channel α Subunit 1 in Dravet Syndrome and the Patients’ Response to Antiepileptic Drugs

By Tian Li


Open access peer-reviewed

5. Altered Potassium Ion Homeostasis in Hearing Loss

By Viktoria Szuts, Janos Andras Jarabin, Nikoletta Nagy, Ferenc Otvos, Roland Nagy, Attila Nagy, Katalin Halasy, Laszlo Rovo, Marta Szell and Jozsef Geza Kiss


Open access peer-reviewed

6. Role of Calcium Permeable Channels in Pain Processing

By Célio Castro-Junior, Luana Ferreira, Marina Delgado, Juliana Silva and Duana Santos


Open access peer-reviewed

7. L-Type Calcium Channels: Structure and Functions

By Tianhua Feng, Subha Kalyaanamoorthy and Khaled Barakat


Open access peer-reviewed

8. TRP Ion Channels: From Distribution to Assembly

By Wei Cheng


Open access peer-reviewed

9. Lifting the Fog over Mitochondrial Chloride Channels

By Katarina Mackova, Anton Misak and Zuzana Tomaskova


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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