Open access peer-reviewed Edited Volume

Protein Interactions

Edited by Jianfeng Cai

University of South Florida, United States of America


Protein interactions, which include interactions between proteins and other biomolecules, are essential to all aspects of biological processes, such as cell growth, differentiation, and apoptosis. Therefore, investigation and modulation of protein interactions are of significance as it not only reveals the mechanism governing cellular activity, but also leads to potential agents for the treatment of various diseases. The objective of this book is to highlight some of the latest approaches in the study of protein interactions, including modulation of protein interactions, development of analytical techniques, etc. Collectively they demonstrate the importance and the possibility for the further investigation and modulation of protein interactions as technology is evolving.

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Protein InteractionsEdited by Jianfeng Cai

Published: March 16th 2012

DOI: 10.5772/2336

ISBN: 978-953-51-0244-1

eBook (PDF) ISBN: 978-953-51-5242-2

Copyright year: 2012

Books open for chapter submissions

67425 Total Chapter Downloads

17 Crossref Citations

42 Web of Science Citations

57 Dimensions Citations


Open access peer-reviewed

1. MOZ-TIF2 Fusion Protein Binds to Histone Chaperon Proteins CAF-1A and ASF1B Through Its MOZ Portion

By Hong Yin, Jonathan Glass and Kerry L. Blanchard


Open access peer-reviewed

2. Autophagy-Mediated Defense Response of Mouse Mesenchymal Stromal Cells (MSCs) to Challenge with Escherichia coli

By N.V. Gorbunov, B.R. Garrison, M. Zhai, D.P. McDaniel, G.D. Ledney, T.B. Elliott and J.G. Kiang


Open access peer-reviewed

3. The Use of Reductive Methylation of Lysine Residues to Study Protein-Protein Interactions in High Molecular Weight Complexes by Solution NMR

By Youngshim Lee, Sherwin J. Abraham and Vadim Gaponenko


Open access peer-reviewed

4. Regulation of Protein-Protein Interactions by the SUMO and Ubiquitin Pathways

By Yifat Yanku and Amir Orian


Open access peer-reviewed

5. Functional Protein Interactions in Steroid Receptor-Chaperone Complexes

By Thomas Ratajczak, Rudi K. Allan, Carmel Cluning and Bryan K. Ward


Open access peer-reviewed

6. The TPR Motif as a Protein Interaction Module - A Discussion of Structure and Function

By Natalie Zeytuni and Raz Zarivach


Open access peer-reviewed

7. The Two DUF642 At5g11420 and At4g32460-Encoded Proteins Interact In Vitro with the AtPME3 Catalytic Domain

By Esther Zúñiga-Sánchez and Alicia Gamboa-de Buen


Open access peer-reviewed

8. Protein-Protein Interactions and Disease

By Aditya Rao, Gopalakrishnan Bulusu, Rajgopal Srinivasan and Thomas Joseph


Open access peer-reviewed

9. AApeptides as a New Class of Peptidomimetics to Regulate Protein-Protein Interactions

By Youhong Niu, Yaogang Hu, Rongsheng E. Wang, Xiaolong Li, Haifan Wu, Jiandong Chen and Jianfeng Cai


Open access peer-reviewed

10. Protein Interactions in S-RNase-Based Gametophytic Self-Incompatibility

By Thomas L. Sims


Open access peer-reviewed

11. Direct Visualization of Single-Molecule DNA-Binding Proteins Along DNA to Understand DNA-Protein Interactions

By Hiroaki Yokota


Open access peer-reviewed

12. Defining the Cellular Interactome of Disease-Linked Proteins in Neurodegeneration

By Verena Arndt and Ina Vorberg


Open access peer-reviewed

13. Biochemical, Structural and Pathophysiological Aspects of Prorenin and (Pro)renin Receptor

By A.H.M. Nurun Nabi and Fumiaki Suzuki


Open access peer-reviewed

14. Cholesterol-Binding Peptides and Phagocytosis

By Antonina Dunina-Barkovskaya


Open access peer-reviewed

15. One-by-One Sample Preparation Method for Protein Network Analysis

By Shun-Ichiro Iemura and Tohru Natsume


Open access peer-reviewed

16. Live In-Cell Visualization of Proteins Using Super Resolution Imaging

By Catherine H. Kaschula, Dirk Lang and M. Iqbal Parker


Open access peer-reviewed

17. Approaches to Analyze Protein-Protein Interactions of Membrane Proteins

By Sabine Hunke and Volker S. Müller


Open access peer-reviewed

18. Relating Protein Structure and Function Through a Bijection and Its Implications on Protein Structure Prediction

By Marco Ambriz-Rivas, Nina Pastor and Gabriel del Rio


Open access peer-reviewed

19. Protein-DNA Interactions Studies with Single Tethered Molecule Techniques

By Guy Nir, Moshe Lindner and Yuval Garini


Open access peer-reviewed

20. Characterization of Protein-Protein Interactions via Static and Dynamic Light Scattering

By Daniel Some and Sophia Kenrick


Open access peer-reviewed

21. Site-Directed Spin Labeling and Electron Paramagnetic Resonance (EPR) Spectroscopy: A Versatile Tool to Study Protein-Protein Interactions

By Johann P. Klare


Open access peer-reviewed

22. Modification, Development, Application and Prospects of Tandem Affinity Purification Method

By Xiaoli Xu, Xueyong Li, Hua Zhang and Lizhe An


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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