Open access peer-reviewed Edited Volume

Embryonic Stem Cells

Differentiation and Pluripotent Alternatives

Edited by Michael S. Kallos

University of Calgary, Canada

The ultimate clinical implementation of embryonic stem cells will require methods and protocols to turn these unspecialized cells into the fully functioning cell types found in a wide variety of tissues and organs. In order to achieve this, it is necessary to clearly understand the signals and cues that direct embryonic stem cell differentiation. This book provides a snapshot of current research on the differentiation of embryonic stem cells to a wide variety of cell types, including neural, cardiac, endothelial, osteogenic, and hepatic cells. In addition, induced pluripotent stem cells and other pluripotent stem cell sources are described. The book will serve as a valuable resource for engineers, scientists, and clinicians as well as students in a wide range of disciplines.

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Embryonic Stem CellsDifferentiation and Pluripotent AlternativesEdited by Michael S. Kallos

Published: October 12th 2011

DOI: 10.5772/1789

ISBN: 978-953-307-632-4

eBook (PDF) ISBN: 978-953-51-6521-7

Copyright year: 2011

Books open for chapter submissions

58182 Total Chapter Downloads

4 Crossref Citations

25 Web of Science Citations

31 Dimensions Citations


Open access peer-reviewed

1. Role of Signaling Pathways and Epigenetic Factors in Lineage Determination During Human Embryonic Stem Cell Differentiation

By Prasenjit Sarkar and Balaji M. Rao


Open access peer-reviewed

2. Bioactive Lipids in Stem Cell Differentiation

By Erhard Bieberich and Guanghu Wang


Open access peer-reviewed

3. Retinoid Signaling is a Context-Dependent Regulator of Embryonic Stem Cells

By Zoltan Simandi and Laszlo Nagy


Open access peer-reviewed

4. Pluripotent Stem Cells as an In Vitro Model of Neuronal Differentiation

By Irina Kerkis, Mirian A. F. Hayashi, Nelson F. Lizier, Antonio C. Cassola, Lygia V. Pereira and Alexandre Kerkis


Open access peer-reviewed

5. Characterization of Embryonic Stem (ES) Neuronal Differentiation Combining Atomic Force, Confocal and DIC Microscopy Imaging

By Maria Elisabetta Ruaro, Jelena Ban and Vincent Torre


Open access peer-reviewed

6. Oligodendrocyte Fate Determination in Human Embryonic Stem Cells

By Siddharth Gupta, Angelo All and Candace Kerr


Open access peer-reviewed

7. Stem-Cell Therapy for Retinal Diseases

By Rubens Camargo Siqueira


Open access peer-reviewed

8. Transcriptional Networks of Embryonic Stem Cell-Derived Cardiomyogenesis

By Diego Franco, Estefania Lozano-Velasco and Amelia Aránega


Open access peer-reviewed

9. Human Pluripotent Stem Cells in Cardiovascular Research and Regenerative Medicine

By Ellen Poon, Chi-wing Kong and Ronald A. Li


Open access peer-reviewed

10. Human Pluripotent Stem Cell-Derived Cardiomyocytes: Maturity and Electrophysiology

By Ville Kujala, Mari Pekkanen-Mattila and Katriina Aalto-Setäla


Open access peer-reviewed

11. Maintenance Of Calcium Homeostasis in Embryonic Stem Cell-Derived Cardiomyocytes

By Iek Chi Lo, Chun Kit Wong and Suk Ying Tsang


Open access peer-reviewed

12. Myogenic Differentiation of ES Cells for Therapies in Neuromuscular Diseases: Progress to Date

By Camila F. Almeida, Danielle Ayub-Guerrieri and Mariz Vainzof


Open access peer-reviewed

13. Dissecting the Signal Transduction Pathway that Directs Endothelial Differentiation Using Embryonic Stem Cell-Derived Vascular Progenitor Cells

By Kyoko Kawasaki and Keiji Miyazawa


Open access peer-reviewed

14. Endothelial Differentiation of Embryonic Stem Cells

By Peter Oettgen


Open access peer-reviewed

15. Stem Cells for HUMAN Hepatic Tissue Engineering

By N.I. Nativ, M.A. Ghodbane, T.J. Maguire, F. Berthiaume and M.L. Yarmush


Open access peer-reviewed

16. Hepatic Differentiation of Human Embryonic and Induced Pluripotent Stem Cells for Regenerative Medicine

By Toshio Miki


Open access peer-reviewed

17. Osteogenesis from Pluripotent Stem Cells: Neural Crest or Mesodermal Origin?

By Kevin C. Keller and Nicole I. zur Nieden


Open access peer-reviewed

18. The Past, Present and Future of Induced Pluripotent Stem Cells

By Koji Tanabe and Kazutoshi Takahashi


Open access peer-reviewed

19. New Techniques in the Generation of Induced Pluripotent Stem Cells

By Raymond C.B. Wong, Ellen L. Smith and Peter J. Donovan


Open access peer-reviewed

20. Generation of ICM-Type Human iPS Cells from CD34+ Cord Blood Cells

By Naoki Nishishita, Noemi Fusaki and Shin Kawamata


Open access peer-reviewed

21. Modelling of Neurological Diseases Using Induced Pluripotent Stem Cells

By Oz Pomp, Chen Sok Lam, Hui Theng Gan, Srinivas Ramasamy and Sohail Ahmed


Open access peer-reviewed

22. Very Small Embryonic/Epiblast-Like Stem Cells (VSELs) Residing in Adult Tissues and Their Role in Tissue Rejuvenation and Regeneration

By Dong-Myung Shin, Janina Ratajczak, Magda Kucia and Mariusz Z. Ratajczak


Open access peer-reviewed

23. Multipotent Dental Stem Cells: An Alternative Adult Derived Stem Cell Source for Regenerative Medicine

By Tammy Laberge and Herman S. Cheung


Open access peer-reviewed

24. Pluripotent Stem Cells from Testis

By Sandeep Goel and Hiroshi Imai


Open access peer-reviewed

25. Amniotic Fluid Stem Cells

By Gianni Carraro, Orquidea H. Garcia, Laura Perin, Roger De Filippo and David Warburton


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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