Open access peer-reviewed Edited Volume

Neural Stem Cells

New Perspectives

Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open. On one side, deep characterization of neural stem and progenitor cells, their niches, and their progeny in brain neurogenic sites overtly showed that new neurons can be generated in the brain of adult mammals, including humans. On the other side, many problems arise when stem cells encounter the mature brain parenchyma, still hampering the development of efficacious therapeutic approaches with endogenous or exogenously-delivered neural stem cells. This book tries to make the point on these extremely promising, yet unresolved, issues.

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Neural Stem CellsNew PerspectivesEdited by Luca Bonfanti

Published: April 24th 2013

DOI: 10.5772/56573

ISBN: 978-953-51-1069-9

eBook (PDF) ISBN: 978-953-51-7133-1

Copyright year: 2013

Books open for chapter submissions

22313 Total Chapter Downloads

7 Crossref Citations

13 Web of Science Citations

27 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Systems for ex-vivo Isolation and Culturing of Neural Stem Cells

By Simona Casarosa, Jacopo Zasso and Luciano Conti

1915

Open access peer-reviewed

2. Neural Stem Cell Heterogeneity

By Verdon Taylor

1016

Open access peer-reviewed

3. Diversity of Neural Stem/Progenitor Populations: Varieties by Age, Regional Origin and Environment

By Emília Madarász

2797

Open access peer-reviewed

4. Reactive Muller Glia as Potential Retinal Progenitors

By Teri L. Belecky-Adams, Ellen C. Chernoff, Jonathan M. Wilson and Subramanian Dharmarajan

1963

Open access peer-reviewed

5. Neural Stem Cell: Tools to Unravel Pathogenetic Mechanisms and to Test Novel Drugs for CNS Diseases

By Luca Colucci-D'Amato and MariaTeresa Gentile

960

Open access peer-reviewed

6. Postnatal Neurogenesis in the Subventricular Zone: A Manipulable Source for CNS Plasticity and Repair

By Manavendra Pathania and Angelique Bordey

1020

Open access peer-reviewed

7. Modulation of Adult Neurogenesis by the Nitric Oxide System

By Bruno P. Carreira, Ana I. Santos, Caetana M. Carvalho and Inês M. Araújo

1369

Open access peer-reviewed

8. A Vascular Perspective on Neurogenesis

By Joshua S. Goldberg and Karen K. Hirschi

2080

Open access peer-reviewed

9. Parenchymal Neuro-Glio-Genesis Versus Germinal Layer- Derived Neurogenesis: Two Faces of Central Nervous System Structural Plasticity

By Luca Bonfanti, Giovanna Ponti, Federico Luzzati, Paola Crociara, Roberta Parolisi and Maria Armentano

1376

Open access peer-reviewed

10. A Survey of the Molecular Basis for the Generation of Functional Dopaminergic Neurons from Pluripotent Stem Cells: Insights from Regenerative Biology and Regenerative Medicine

By Kaneyasu Nishimura, Yoshihisa Kitamura, Kiyokazu Agata and Jun Takahashi

1069

Open access peer-reviewed

11. Systemic Neural Stem Cell-Based Therapeutic Interventions for Inflammatory CNS Disorders

By Matteo Donegà, Elena Giusto, Chiara Cossetti and Stefano Pluchino

1885

Open access peer-reviewed

12. Cell Adhesion Molecules in Neural Stem Cell and Stem Cell- Based Therapy for Neural Disorders

By Shan Bian

2318

Open access peer-reviewed

13. Neuroinflammation on the Epigenetics of Neural Stem Cells

By Nando Dulal Das and Young Gyu Chai

1279

Open access peer-reviewed

14. Primary Neural Stem Cell Cultures from Adult Pig Brain and Their Nerve-Regenerating Properties: Novel Strategies for Cell Therapy

By Olivier Liard and Emmanuel Moyse

1267

Edited Volume and chapters are indexed in

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