Open access peer-reviewed Edited volume

DNA Replication

Current Advances

The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.

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DNA ReplicationCurrent AdvancesEdited by Herve Seligmann

Published: August 1st 2011

DOI: 10.5772/791

ISBN: 978-953-307-593-8

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Open access peer-reviewed

1. DNA Structure: Alphabet Soup for the Cellular Soul

By P. Shing Ho and Megan Carter

5639

Open access peer-reviewed

2. Replication Demands an Amendment of the Double Helix

By You Cheng Xu

2952

Open access peer-reviewed

3. Phosphorothioation: An Unusual Post-Replicative Modification on the DNA Backbone

By Lianrong Wang, Shi Chen and Zixin Deng

1924

Open access peer-reviewed

4. Mitosis and DNA Replication and Life Origination Hydrate Hypotheses: Common Physical and Chemical Grounds

By Ostrovskii Victor E. and Kadyshevich Elena A.

1902

Open access peer-reviewed

5. Strand-specific Composition Bias in Bacterial Genomes

By Feng-Biao Guo and Lu-Wen Ning

1849

Open access peer-reviewed

6. Mutation Patterns Due to Converging Mitochondrial Replication and Transcription Increase Lifespan, and Cause Growth Rate-Longevity Tradeoffs

By Hervé Seligmann

1424

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7. Mitochondrial DNA Replication in Health and Disease

By Nadezda Apostolova and Juan V. Esplugues

2307

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8. Damage and Replication Stress Responses

By Haiying Wang, Ping Shen and Wei-Guo Zhu

2298

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9. Relationship between Fork Progression and Initiation of Chromosome Replication in E. coli

By Elena C. Guzmán, Israel Salguero, Carmen Mata Martín, Elena López Acedo, Estrella Guarino, Ma Antonia Sánchez-Romero, Vic Norris and Alfonso Jiménez-Sánchez

1402

Open access peer-reviewed

10. Replication Origin Selection and Pre-Replication Complex Assembly

By Kusic-Tisma Jelena and Stefanovic Dragana

2123

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11. The Coordination between DNA Replication Initiation and Other Cell Cycle Events

By Shijiao Huang and Chuanmao Zhang

2684

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12. The Organisation of Replisomes

By Anna Ligasová and Karel Koberna

2306

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13. Eukaryotic Replication Barriers: How, Why and Where Forks Stall

By Jacob Z. Dalgaard, Emma L. Godfrey and Ramsay J. MacFarlane

2829

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14. Control of Telomeric DNA Replication: Genetics, Molecular Biology, and Physiology

By Akira Matsuura and Aiko Matsui

3473

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15. Telomere Maintenance in Organisms without Telomerase

By James M. Mason, Hemakumar M. Reddy and Radmila Capkova Frydrychova

2521

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16. Eukaryote DNA Replication and Recombination: an Intimate Association

By Ramsay J. McFarlane, Khalid Al-Zeer and Jacob Z. Dalgaard

1961

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17. Cell Cycle Regulation of DNA Replication in S. cerevisiae

By Jorrit M. Enserink

2951

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18. Free Histones and the Cell Cycle

By Douglas Maya, Macarena Morillo-Huesca, Sebastián Chávez and Mari-Cruz Muñoz-Centeno

4289

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19. Involvement of Linker Histones in the Regulation of Replication Timing

By Christophe Thiriet, Gwenola Auda-Boucher and Yvonnick Chéraud

1357

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20. Replication Timing: Evolution, Nuclear Organization and Relevance for Human Disease

By Megan Lynne Wright and Frank Grützner

1868

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21. The Silencing Face of DNA Replication: Gene Repression Mediated by DNA Replication Factors

By Patricia Chisamore-Robert, Daniel Jeffery and Krassimir Yankulov

1385

Open access peer-reviewed

22. Faithful DNA Replication Requires Regulation of CDK Activity by Checkpoint Kinases

By Claus Storgaard Sørensen, Halfdan Beck, Viola Nähse-Kumpf and Randi G. Syljuåsen

1682

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23. Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication

By Loyer Pascal and Corlu Anne

1736

Open access peer-reviewed

24. Binding of Human MCM-BP with MCM2-7 Proteins

By Ryoko Kon, Shunsuke Kusunoki, Naohito Nozaki and Yukio Ishimi

1529

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25. DNA Replication in Animal Systems Lacking Thioredoxin Reductase I

By Edward E. Schmidt

1700

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26. Prevalence of Reactivation of Hepatitis B Virus DNA Replication in Rheumatoid Arthritis Patients

By Yukitomo Urata, Ryoko Uesato and Dai Tanaka

2227

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27. Oncogenic Aspects of HPV Infections of the Female Genital Tract

By Josko Zekan, Maja Sirotkovic-Skerlev and Mihael Skerlev

1955

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28. The Role of E2 Proteins in Papillomavirus DNA Replication

By Reet Kurg

5046

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29. Topoisomerase I and II Expression in Recurrent Colorectal Cancer Cells: A Dubious Matter

By Panagiotis Gouveris, Elias Skopelitis and Nicolas Tsavaris

1785

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30. Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions

By Felix Wussow, Tanja Spieckermann, Anne Brunnemann, Linda Hüske, Tuna Toptan and Helmut Fickenscher

1969

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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