Open access peer-reviewed Edited volume

DNA Replication

Current Advances

The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.

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DNA ReplicationCurrent AdvancesEdited by Herve Seligmann

Published: August 1st 2011

DOI: 10.5772/791

ISBN: 978-953-307-593-8

Books open for chapter submissions

72223 Total Chapter Downloads

12 Crossref Citations

55 Web of Science Citations

63 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. DNA Structure: Alphabet Soup for the Cellular Soul

By P. Shing Ho and Megan Carter

5720

Open access peer-reviewed

2. Replication Demands an Amendment of the Double Helix

By You Cheng Xu

3010

Open access peer-reviewed

3. Phosphorothioation: An Unusual Post-Replicative Modification on the DNA Backbone

By Lianrong Wang, Shi Chen and Zixin Deng

1963

Open access peer-reviewed

4. Mitosis and DNA Replication and Life Origination Hydrate Hypotheses: Common Physical and Chemical Grounds

By Ostrovskii Victor E. and Kadyshevich Elena A.

1954

Open access peer-reviewed

5. Strand-specific Composition Bias in Bacterial Genomes

By Feng-Biao Guo and Lu-Wen Ning

1884

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6. Mutation Patterns Due to Converging Mitochondrial Replication and Transcription Increase Lifespan, and Cause Growth Rate-Longevity Tradeoffs

By Hervé Seligmann

1450

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7. Mitochondrial DNA Replication in Health and Disease

By Nadezda Apostolova and Juan V. Esplugues

2353

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8. Damage and Replication Stress Responses

By Haiying Wang, Ping Shen and Wei-Guo Zhu

2328

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9. Relationship between Fork Progression and Initiation of Chromosome Replication in E. coli

By Elena C. Guzmán, Israel Salguero, Carmen Mata Martín, Elena López Acedo, Estrella Guarino, Ma Antonia Sánchez-Romero, Vic Norris and Alfonso Jiménez-Sánchez

1419

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10. Replication Origin Selection and Pre-Replication Complex Assembly

By Kusic-Tisma Jelena and Stefanovic Dragana

2148

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11. The Coordination between DNA Replication Initiation and Other Cell Cycle Events

By Shijiao Huang and Chuanmao Zhang

2717

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12. The Organisation of Replisomes

By Anna Ligasová and Karel Koberna

2344

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13. Eukaryotic Replication Barriers: How, Why and Where Forks Stall

By Jacob Z. Dalgaard, Emma L. Godfrey and Ramsay J. MacFarlane

2898

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14. Control of Telomeric DNA Replication: Genetics, Molecular Biology, and Physiology

By Akira Matsuura and Aiko Matsui

3504

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15. Telomere Maintenance in Organisms without Telomerase

By James M. Mason, Hemakumar M. Reddy and Radmila Capkova Frydrychova

2551

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16. Eukaryote DNA Replication and Recombination: an Intimate Association

By Ramsay J. McFarlane, Khalid Al-Zeer and Jacob Z. Dalgaard

1988

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17. Cell Cycle Regulation of DNA Replication in S. cerevisiae

By Jorrit M. Enserink

2982

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18. Free Histones and the Cell Cycle

By Douglas Maya, Macarena Morillo-Huesca, Sebastián Chávez and Mari-Cruz Muñoz-Centeno

4349

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19. Involvement of Linker Histones in the Regulation of Replication Timing

By Christophe Thiriet, Gwenola Auda-Boucher and Yvonnick Chéraud

1381

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20. Replication Timing: Evolution, Nuclear Organization and Relevance for Human Disease

By Megan Lynne Wright and Frank Grützner

1895

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21. The Silencing Face of DNA Replication: Gene Repression Mediated by DNA Replication Factors

By Patricia Chisamore-Robert, Daniel Jeffery and Krassimir Yankulov

1401

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22. Faithful DNA Replication Requires Regulation of CDK Activity by Checkpoint Kinases

By Claus Storgaard Sørensen, Halfdan Beck, Viola Nähse-Kumpf and Randi G. Syljuåsen

1729

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23. Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication

By Loyer Pascal and Corlu Anne

1779

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24. Binding of Human MCM-BP with MCM2-7 Proteins

By Ryoko Kon, Shunsuke Kusunoki, Naohito Nozaki and Yukio Ishimi

1562

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25. DNA Replication in Animal Systems Lacking Thioredoxin Reductase I

By Edward E. Schmidt

1746

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26. Prevalence of Reactivation of Hepatitis B Virus DNA Replication in Rheumatoid Arthritis Patients

By Yukitomo Urata, Ryoko Uesato and Dai Tanaka

2251

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27. Oncogenic Aspects of HPV Infections of the Female Genital Tract

By Josko Zekan, Maja Sirotkovic-Skerlev and Mihael Skerlev

1988

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28. The Role of E2 Proteins in Papillomavirus DNA Replication

By Reet Kurg

5086

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29. Topoisomerase I and II Expression in Recurrent Colorectal Cancer Cells: A Dubious Matter

By Panagiotis Gouveris, Elias Skopelitis and Nicolas Tsavaris

1854

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30. Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions

By Felix Wussow, Tanja Spieckermann, Anne Brunnemann, Linda Hüske, Tuna Toptan and Helmut Fickenscher

1989

Edited volume and chapters are indexed in

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  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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