Open access peer-reviewed Edited Volume

Protein Phosphorylation in Human Health

Edited by Cai Huang

University of Kentucky, United States of America

15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.

Order hardcopy
Protein Phosphorylation in Human HealthEdited by Cai Huang

Published: September 6th 2012

DOI: 10.5772/2944

ISBN: 978-953-51-0737-8

eBook (PDF) ISBN: 978-953-51-5315-3

Copyright year: 2012

Books open for chapter submissions

48847 Total Chapter Downloads

43 Crossref Citations

60 Web of Science Citations

91 Dimensions Citations


Open access peer-reviewed

1. Protein Phosphorylation as a Key Mechanism of mTORC1/2 Signaling Pathways

By Elena Tchevkina and Andrey Komelkov


Open access peer-reviewed

2. Sestrins Link Tumor Suppressors with the AMPK-TOR Signaling Network

By Andrei V. Budanov


Open access peer-reviewed

3. Regulation of Autophagy by Protein Phosphorylation

By Björn Stork, Sebastian Alers, Antje S. Löffler and Sebastian Wesselborg


Open access peer-reviewed

4. Fatty Acids Stimulate Glucose Uptake by the PI3K/AMPK/Akt and PI3K/ERK1/2 Pathways

By Jing Pu and Pingsheng Liu


Open access peer-reviewed

5. RNA Polymerase II Phosphorylation and Gene Expression Regulation

By Olga Calvo and Alicia García


Open access peer-reviewed

6. The Prp4 Kinase: Its Substrates, Function and Regulation in Pre-mRNA Splicing

By Martin Lützelberger and Norbert F. Käufer


Open access peer-reviewed

7. More Than Just an OFF-Switch: The Essential Role of Protein Dephosphorylation in the Modulation of BDNF Signaling Events

By Katrin Deinhardt and Freddy Jeanneteau


Open access peer-reviewed

8. Signalling DNA Damage

By Andres Joaquin Lopez-Contreras and Oscar Fernandez-Capetillo


Open access peer-reviewed

9. Tyrosine Phosphorylation of the NMDA Receptor Following Cerebral Ischaemia

By Dmytro Pavlov and John G. Mielke


Open access peer-reviewed

10. Function of Flotillins in Receptor Tyrosine Kinase Signaling and Endocytosis: Role of Tyrosine Phosphorylation and Oligomerization

By Nina Kurrle, Bincy John, Melanie Meister and Ritva Tikkanen


Open access peer-reviewed

11. Role of Tyrosine Kinase A Receptor (TrkA) on Pathogenicity of Clostridium perfringens Alpha-Toxin

By Masataka Oda, Masahiro Nagahama, Keiko Kobayashi and Jun Sakurai


Open access peer-reviewed

12. Modulation of HER2 Tyrosine/Threonine Phosphorylation and Cell Signalling

By Yamuna D. Gandaharen, Rachel S. Welt, David Kostyal and Sydney Welt


Open access peer-reviewed

13. Protein Phosphorylation is an Important Tool to Change the Fate of Key Players in the Control of Cell Cycle Progression in Saccharomyces cerevisiae

By Roberta Fraschini, Erica Raspelli and Corinne Cassani


Open access peer-reviewed

14. Phosphorylation Mediated Regulation of Cdc25 Activity, Localization and Stability

By C. Frazer and P.G. Young


Open access peer-reviewed

15. Bacterial Two-Component Systems: Structures and Signaling Mechanisms

By Shuishu Wang


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£139

Order now

Residents of European Union countries need to add a Book Value-Added Tax Rate based on their country of residence. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase