Open access peer-reviewed Edited Volume

DNA Repair

On the Pathways to Fixing DNA Damage and Errors

DNA repair is fundamental to all cell types to maintain genomic stability. A collection of cutting-edge reviews, DNA Repair - On the pathways to fixing DNA damage and errors covers major aspects of the DNA repair processes in a large variety of organisms, emphasizing foremost developments, questions to be solved and new directions in this rapidly evolving area of modern biology. Written by researchers at the vanguard of the DNA repair field, the chapters highlight the importance of the DNA repair mechanisms and their linkage to DNA replication, cell-cycle progression and DNA recombination. Major topics include: base excision repair, nucleotide excision repair, mismatch repair, double-strand break repair, with focus on specific inhibitors and key players of DNA repair such as nucleases, ubiquitin-proteasome enzymes, poly ADP-ribose polymerase and factors relevant for DNA repair in mitochondria and embryonic stem cells. This book is a journey into the cosmos of DNA repair and its frontiers.

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DNA RepairOn the Pathways to Fixing DNA Damage and ErrorsEdited by Francesca Storici

Published: September 9th 2011

DOI: 10.5772/871

ISBN: 978-953-307-649-2

eBook (PDF) ISBN: 978-953-51-5160-9

Copyright year: 2011

Books open for chapter submissions

48123 Total Chapter Downloads

14 Crossref Citations

45 Web of Science Citations

47 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Lagging Strand Synthesis and Genomic Stability

By Tuan Anh Nguyen, Chul-Hwan Lee and Yeon-Soo Seo

3011

Open access peer-reviewed

2. Synergy Between DNA Replication and Repair Mechanisms

By Maria Zannis-Hadjopoulos and Emmanouil Rampakakis

2782

Open access peer-reviewed

3. New Insight on Entangled DNA Repair Pathways: Stable Silenced Human Cells for Unraveling the DDR Jigsaw

By Biard Denis S.F.

2269

Open access peer-reviewed

4. Base Excision Repair Pathways

By Christina Emmanouil

3387

Open access peer-reviewed

5. Repair of Viral Genomes by Base Excision Pathways: African Swine Fever Virus as a Paradigm

By Modesto Redrejo-Rodríguez, Javier M. Rodríguez, José Salas and María L. Salas

2220

Open access peer-reviewed

6. Nucleotide Excision Repair in S. cerevisiae

By Danielle Tatum and Shisheng Li

2137

Open access peer-reviewed

7. Biochemical Properties of MutL, a DNA Mismatch Repair Endonuclease

By Kenji Fukui, Atsuhiro Shimada, Hitoshi Iino, Ryoji Masui and Seiki Kuramitsu

2850

Open access peer-reviewed

8. The Pathways of Double-Strand Break Repair

By Emil Mladenov and George Iliakis

4409

Open access peer-reviewed

9. Human CtIP and Its Homologs: Team Players in DSB Resection Games

By Yasuhiro Tsutsui, Akihito Kawasaki and Hiroshi Iwasaki

2720

Open access peer-reviewed

10. Archaeal DNA Repair Nucleases

By Roxanne Lestini, Christophe Creze, Didier Flament, Hannu Myllykallio and Ghislaine Henneke

2590

Open access peer-reviewed

11. Nucleases of Metallo-Beta-Lactamase and Protein Phosphatase Families in DNA Repair

By Francisco J Fernandez, Miguel Lopez-Estepa and M. Cristina Vega

2198

Open access peer-reviewed

12. Mammalian Spermatogenesis, DNA Repair, Poly(ADP-ribose) Turnover: the State of the Art

By Maria Rosaria Faraone Mennella

3019

Open access peer-reviewed

13. The Ubiquitin-Proteasome System and DNA Repair

By Christine A. Falaschetti, Emily C. Mirkin, Sumita Raha, Tatjana Paunesku and Gayle E. Woloschak

3131

Open access peer-reviewed

14. Virtual Screening for DNA Repair Inhibitors

By Barakat, K. and Tuszynski, J.

2307

Open access peer-reviewed

15. Mitochondrial DNA Repair

By Sarah A. Martin

2732

Open access peer-reviewed

16. Mitochondrial DNA Damage, Repair, Degradation and Experimental Approaches to Studying These Phenomena

By Inna Shokolenko, Susan LeDoux, Glenn Wilson and Mikhail Alexeyev

3452

Open access peer-reviewed

17. DNA Repair in Embryonic Stem Cells

By Volker Middel and Christine Blattner

2914

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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