Open access peer-reviewed Edited Volume

Anticoagulation Therapy

Edited by Ozcan Basaran

Muğla University


Murat Biteker

Muğla University

The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.

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Anticoagulation TherapyEdited by Ozcan Basaran

Published: September 8th 2016

DOI: 10.5772/61447

ISBN: 978-953-51-2667-6

Print ISBN: 978-953-51-2666-9

eBook (PDF) ISBN: 978-953-51-7309-0

Copyright year: 2016

Books open for chapter submissions

12141 Total Chapter Downloads

5 Crossref Citations

3 Web of Science Citations

10 Dimensions Citations


Open access peer-reviewed

1. Biochemistry and Stereochemistry of Anticoagulants

By Ioana-Daria Tiuca


Open access peer-reviewed

2. Comparative Biology of the Resistance to Vitamin K Antagonists: An Overview of the Resistance Mechanisms

By Sébastien Lefebvre, Etienne Benoit and Virginie Lattard


Open access peer-reviewed

3. The Risk Factors of Thrombogenic, Thrombophilia, and the Principle for Heparin Prophylaxis in Personalized Medicine

By Andrey Momot, Irina Taranenko, Lyudmila Tsyvkina, Nadezhda Semenova and Irina Molchanova


Open access peer-reviewed

4. Management of Anticoagulation Around Cardiac Implantable Electronic Device Surgery

By Roberto T. Sant´Anna, Tiago Luiz L. Leirira, Pedro T. Sant´Anna and Gustavo G. Lima


Open access peer-reviewed

5. Prothrombin Complex Concentrate, a General Antidote for Oral Anticoagulation

By Herm Jan M. Brinkman


Open access peer-reviewed

6. Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation: Pharmacology and Phase III Clinical Trials

By Keval K. Patel, Ali A. Mehdirad and Richard Lee


Open access peer-reviewed

7. Non–Vitamin K Antagonist Oral Anticoagulants, Clinical Use, Real-World Data, and Reversal of Anticoagulant Effect

By Özcan Başaran, Volkan Doğan, Ibrahim Altun and Murat Biteker


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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