Open access peer-reviewed Edited Volume

The Clinical Spectrum of Alzheimer's Disease

The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies

Edited by Suzanne De La Monte

Brown University, United States of America

The Clinical Spectrum of Alzheimer's Disease: The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies is highly informative and current. Acknowledged experts in the field critically review both standard and under-appreciated clinical, behavioral, epidemiological, genetic, and neuroimaging attributes of Alzheimer's disease. The collection covers diverse topics of interest to clinicians and researchers alike. Experienced professionals and newcomers to the field will benefit from the read. The strengths and weaknesses of current clinical, non-invasive, neuro-imaging, and biomarker diagnostic approaches are explained. The perspectives give fresh insights into the process of neurodegeneration. Readers will be enlightened by the evidence that the neural circuits damaged by neurodegeneration are much broader than conventionally taught, suggesting that Alzheimer's could be detected at earlier stages of disease by utilizing multi-pronged diagnostic approaches. This book inspires renewed hope that more effective treatments could be developed based upon the expanding list of potential therapeutic targets.

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The Clinical Spectrum of Alzheimer's DiseaseThe Charge Toward Comprehensive Diagnostic and Therapeutic StrategiesEdited by Suzanne De La Monte

Published: September 6th 2011

DOI: 10.5772/722

ISBN: 978-953-307-993-6

eBook (PDF) ISBN: 978-953-51-6785-3

Copyright year: 2011

Books open for chapter submissions

37437 Total Chapter Downloads

7 Crossref Citations

21 Web of Science Citations

24 Dimensions Citations


Open access peer-reviewed

1. Risk Factors for Disease Progression in Alzheimer's Disease

By Schmidt C, Wolff M, Shalash A and Zerr I


Open access peer-reviewed

2. Alzheimer’s Disease Genomics and Clinical Applications

By Tih-Shih Lee and Mei Sian Chong


Open access peer-reviewed

3. Addressing Risk Factors for Neurocognitive Decline and Alzheimer’s Disease Among African Americans in the Era of Health Disparities

By David L. Mount, Maria Isabel Rego, Alethea Amponsah, Annette Herron, Darin Johnson, Mario Sims, DeMarc Hickson and Sylvia A. Flack


Open access peer-reviewed

4. Focal Cortical Presentations Genetically Proven Alzheimer Disease

By Naeije G, Van den Berge Delphine, Vokaer M, Fery P, Vilain C, Abramowicz M, Van den Broeck M, Van Broeckhoven C and Bier JC


Open access peer-reviewed

5. Spatial Navigation Impairment in Healthy Aging and Alzheimer’s Disease

By Kamil Vlček


Open access peer-reviewed

6. Visual Cognition in Alzheimer’s Disease and Its Functional Implications

By Philip C. Ko and Brandon A. Ally


Open access peer-reviewed

7. Olfactory Dysfunctions in Alzheimer’s Disease

By Iuliana Nicola-Antoniu


Open access peer-reviewed

8. Currently Available Neuroimaging Approaches in Alzheimer Disease (AD) Early Diagnosis

By Laura Ortiz-Terán, Juan MR Santos, María de las Nieves Cabrera Martín and Tomás Ortiz Alonso


Open access peer-reviewed

9. The Clinical Use of SPECT and PET Molecular Imaging in Alzheimer’s Disease

By Varvara Valotassiou, Nikolaos Sifakis, John Papatriantafyllou, George Angelidis and Panagiotis Georgoulias


Open access peer-reviewed

10. Cerebrospinal Fluid Based Diagnosis in Alzheimer’s Disease

By Inga Zerr, Lisa Kaerst, Joanna Gawinecka and Daniela Varges


Open access peer-reviewed

11. Alzheimer’s Diseases: Towards Biomarkers for an Early Diagnosis

By Benaïssa Elmoualij, Ingrid Dupiereux, Jérémie Seguin, Isabelle Quadrio, Willy Zorzi, Armand Perret-Liaudet and Ernst Heinen


Open access peer-reviewed

12. Phospo-PKCs in Abeta1-42-Specific Human T Cells from Alzheimer’s Disease Patients

By Lanuti Paola, Marchisio Marco, Pierdomenico Laura and Miscia Sebastiano


Open access peer-reviewed

13. The Predictive Role of Hyposmia in Alzheimer's Disease

By Alessandra B. Fioretti, Marco Fusetti and Alberto Eibenstein


Open access peer-reviewed

14. Retinal Nerve Fibre Layer Thinning in Alzheimer Disease

By Panitha Jindahra and Gordon T Plant


Open access peer-reviewed

15. Modulation of Signal Transduction Pathways in Senescence-Accelerated Mice P8 Strain: A Useful Tool for Alzheimer’s Disease Research

By José Luis Albasanz, Carlos Alberto Castillo, Marta Barrachina, Isidre Ferrer and Mairena Martín


Open access peer-reviewed

16. Valosin-Containing Protein (VCP) Disease and Familial Alzheimer’s Disease: Contrasts and Overlaps

By CD Smith, M Badadani, A Nalbandian, E Dec, J Vesa, S Donkervoort, B Martin, GD Watts, V Caiozzo and V Kimonis


Open access peer-reviewed

17. Neural Basis of Hyposmia in Alzheimer’s Disease

By Daniel Saiz-Sánchez, Carlos de la Rosa-Prieto, Isabel Úbeda-Bañón and Alino Martínez-Marcos


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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