Open access peer-reviewed Edited Volume

Neurodegenerative Diseases

Edited by Uday Kishore

Brunel University London

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.

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IntechOpen
Neurodegenerative DiseasesEdited by Uday Kishore

Published: May 15th 2013

DOI: 10.5772/45957

ISBN: 978-953-51-1088-0

eBook (PDF) ISBN: 978-953-51-7146-1

Copyright year: 2013

Books open for chapter submissions

67607 Total Chapter Downloads

49 Crossref Citations

50 Web of Science Citations

106 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Alzheimer’s Disease: A Clinical Perspective

By Weili Xu, Anna Marseglia, Camilla Ferrari and Hui-Xin Wang

2966

Open access peer-reviewed

2. Late-Onset Alzheimer's Disease: Risk Factors, Clinical Diagnosis and the Search for Biomarkers

By Marisol Herrera-Rivero

2516

Open access peer-reviewed

3. Role of Protein Aggregation in Neurodegenerative Diseases

By Yusuf Tutar, Aykut Özgür and Lütfi Tutar

3765

Open access peer-reviewed

4. Role of Oxidative Stress in Aβ Animal Model of Alzheimer's Disease: Vicious Circle of Apoptosis, Nitric Oxide and Age

By Ferihan Cetin

2459

Open access peer-reviewed

5. Alterations of Mitochondria and Golgi Apparatus Are Related to Synaptic Pathology in Alzheimer's Disease

By Stavros J. Baloyannis

2462

Open access peer-reviewed

6. Caspases in Alzheimer’s Disease

By Yan Zhang

2249

Open access peer-reviewed

7. Brain Reserve Regulators in Alzheimer’s Disease

By Ivana Delalle

1823

Open access peer-reviewed

8. Cholesterol and Alzheimer's Disease

By Iuliana Nicola-Antoniu

2245

Open access peer-reviewed

9. Emerging Therapeutic Strategies in Alzheimer's Disease

By Tomohiro Chiba

3399

Open access peer-reviewed

10. Dropping the BACE: Beta Secretase (BACE1) as an Alzheimer’s Disease Intervention Target

By Justin Read and Cenk Suphioglu

2986

Open access peer-reviewed

11. QSAR Analysis of Purine-Type and Propafenone-Type Substrates of P-Glycoprotein Targeting β-Amyloid Clearance

By Jie Yang and Jie Chen

1565

Open access peer-reviewed

12. Therapeutic Interventions in Alzheimer Disease

By Analava Mitra and Baishakhi Dey

2754

Open access peer-reviewed

13. Other Dementias

By Abhishek Shastri, Domenico Marco Bonifati and Uday Kishore

1868

Open access peer-reviewed

14. The Role of Epigenetics in Neurodegenerative Diseases

By Luca Lovrečić, Aleš Maver, Maja Zadel and Borut Peterlin

3892

Open access peer-reviewed

15. Plasma Membrane Channels Formed by Connexins or Pannexins in Microglia: Possible Role in the Inflamed Brain

By Juan A. Orellana

2038

Open access peer-reviewed

16. Influence of Obesity on Neurodegenerative Diseases

By Rana Awada , Avinash Parimisetty and Christian Lefebvre d’Hellencourt

2857

Open access peer-reviewed

17. Electro-Physiological Approaches to Monitoring Neuro- Degenerative Diseases

By Manuel J. Rojas, Camilo Orozco and Francisco Olea

1998

Open access peer-reviewed

18. Oxidative Changes and Possible Effects of Polymorphism of Antioxidant Enzymes in Neurodegenerative Disease

By Eva Babusikova, Andrea Evinova, Jozef Hatok, Dusan Dobrota and Jana Jurecekova

3073

Open access peer-reviewed

19. Intermediate Filaments in Neurodegenerative Diseases

By Rodolphe Perrot and Joel Eyer

2076

Open access peer-reviewed

20. Astrocytes Role in Parkinson: A Double-Edged Sword

By Ricardo Cabezas, Marco Fidel Avila, Daniel Torrente, Ramon Santos El-Bachá, Ludis Morales, Janneth Gonzalez and George E. Barreto

4207

Open access peer-reviewed

21. Zinc and Neurodegenerative Diseases

By Masahiro Kawahara, Keiko Konoha, Hironari Koyama, Susumu Ohkawara and Yutaka Sadakane

2646

Open access peer-reviewed

22. Oligodendrocyte Metabolic Stress in Neurodegeneration

By Daniel Radecki and Alexander Gow

2312

Open access peer-reviewed

23. Spinal Muscular Atrophy: Classification, Diagnosis, Background, Molecular Mechanism and Development of Therapeutics

By Faraz Tariq Farooq, Martin Holcik and Alex MacKenzie

3662

Open access peer-reviewed

24. Pharmacological Treatment of Acute Ischemic Stroke

By Humberto Mestre, Yael Cohen-Minian, Daniel Zajarias-Fainsod and Antonio Ibarra

3366

Open access peer-reviewed

25. Cognitive Dysfunction Syndrome in Senior Dogs

By Camilo Orozco Sanabria, Francisco Olea and Manuel Rojas

2425

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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