Open access peer-reviewed Edited Volume


Edited by L. Miguel Martins

MRC Toxicology Unit, United Kingdom


Samantha Loh

MRC Toxicology Unit, United Kingdom

Currently, the human population is on a collision course for a social and economic burden. As a consequence of changing demographics and an increase in human individuals over the age of 60, age-related neurodegenerative disorders are likely to become more prevalent. It is therefore essential to increase our understanding of such neurodegenerative disorders in order to be more pro-active in managing these diseases processes. The focus of this book is to provide a snapshot of recent advancements in the understanding of basic biological processes that modulate the onset and progression of neurodegenerative processes. This is tackled at the molecular, cellular and whole organism level. We hope that some of the recent discoveries outlined in this book will help to better define the basic biological mechanisms behind neurodegenerative processes and, in the long term, help in the development of novel therapeutic approaches.

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NeurodegenerationEdited by L. Miguel Martins

Published: April 11th 2012

DOI: 10.5772/1900

ISBN: 978-953-51-0502-2

eBook (PDF) ISBN: 978-953-51-6961-1

Copyright year: 2012

Books open for chapter submissions

32949 Total Chapter Downloads

10 Crossref Citations

16 Web of Science Citations

18 Dimensions Citations


Open access peer-reviewed

1. SIRT2 (Sirtuin2) - An Emerging Regulator of Neuronal Degeneration

By Tatsuro Koike, Kazuhiko Suzuki and Tomohiro Kawahata


Open access peer-reviewed

2. Structural and Computational Studies of Interactions of Metals with Amyloid Beta

By V. Chandana Epa


Open access peer-reviewed

3. Neuroprotective Effects of Neuropeptide Y and Y2 and Y5 Receptor Agonists In Vitro and In Vivo

By Maria Smialowska and Helena Domin


Open access peer-reviewed

4. Chronic Formaldehyde-Mediated Impairments and Age-Related Dementia

By Junye Miao and Rongqiao He


Open access peer-reviewed

5. Emerging Concepts Linking Mitochondrial Stress Signalling and Parkinson's Disease

By Ana C. Costa, L. Miguel Martins and Samantha H. Y. Loh


Open access peer-reviewed

6. Melanocortins: Anti-Inflammatory and Neuroprotective Peptides

By Carla Caruso, Lila Carniglia, Daniela Durand, Teresa N. Scimonelli and Mercedes Lasaga


Open access peer-reviewed

7. Mechanisms and Patterns of Axonal Loss in Multiple Sclerosis

By Zachary M. Harris and Jacob A. Sloane


Open access peer-reviewed

8. An Overview of Target Specific Neuro-Protective and Neuro-Restorative Strategies

By Ahmad Al Mutairy, Khalaf Al Moutaery, Abdulrahman Al Asmari, Mohammed Arshaduddin and Mohammad Tariq


Open access peer-reviewed

9. Dictyostelium discoideum: Novel Insights into the Cellular Biology of Neurological Disorders

By Michael A. Myre


Open access peer-reviewed

10. Vascular Dementia and Alzheimer's Disease: Is There a Difference?

By Said Ramdane


Open access peer-reviewed

11. Neurofibromatosis - Diagnostic Assessment

By Sónia Costa, Raquel Tojal and Ana Valverde


Open access peer-reviewed

12. Stroke, Epidemiological and Genetical Approach

By Sellama Nadifi and Khalil Hamzi


Open access peer-reviewed

13. The Time Onset of Post Stroke Dementia

By Gian Luigi Lenzi, Giorgio De Benedetto and Marta Altieri


Open access peer-reviewed

14. Idiopathic Parkinson's Disease, Vascular Risk Factors and Cognition: A Critical Review

By Maxime Doiron and Martine Simard


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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