Open access peer-reviewed Edited Volume

Selected Topics in DNA Repair

Edited by Clark Chen

University of California, San Diego, United States of America

This book is intended for students and scientists working in the field of DNA repair, focusing on a number of topics ranging from DNA damaging agents and mechanistic insights to methods in DNA repair and insights into therapeutic strategies. These topics demonstrate how scientific ideas are developed, tested, dialogued, and matured as it is meant to discuss key concepts in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.

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Selected Topics in DNA RepairEdited by Clark Chen

Published: October 26th 2011

DOI: 10.5772/1749

ISBN: 978-953-307-606-5

eBook (PDF) ISBN: 978-953-51-6536-1

Copyright year: 2011

Books open for chapter submissions

68998 Total Chapter Downloads

30 Crossref Citations

74 Web of Science Citations

105 Dimensions Citations


Open access peer-reviewed

1. The DNA-Damage Response to Ionizing Radiation in Human Lymphocytes

By Maddalena Mognato, Mauro Grifalconi, Sabrina Canova, Cristina Girardi and Lucia Celotti


Open access peer-reviewed

2. Interactions by Carcinogenic Metal Compounds with DNA Repair Processes

By Simona Catalani and Pietro Apostoli


Open access peer-reviewed

3. Effect of Oxidative Stress on DNA Repairing Genes

By Bedia Cakmakoglu, Zeynep Birsu Cincin and Makbule Aydin


Open access peer-reviewed

4. UV Damaged DNA Repair & Tolerance in Plants

By Ashwin L. Ganpudi and Dana F. Schroeder


Open access peer-reviewed

5. DNA Helix Destabilization by Alkylating Agents: From Covalent Bonding to DNA Repair

By Gaëlle Lenglet, Sabine Depauw, Denise Mendy-Belaiche and Marie-Hélène David-Cordonnier


Open access peer-reviewed

6. DNA Damage Caused by Polycyclic Aromatic Hydrocarbons: Mechanisms and Markers

By Balam Muñoz and Arnulfo Albores


Open access peer-reviewed

7. DNA Repair: Lessons from the Evolution of Ionizing- Radiation-Resistant Prokaryotes – Fact and Theory

By Haïtham Sghaier


Open access peer-reviewed

8. Involvement of Non-Homologous End-Joining in Radiation-Induced Genomic Instability

By Keiji Suzuki, Motohiro Yamauchi, Masatoshi Suzuki, Yasuyoshi Oka and Shunichi Yamashita


Open access peer-reviewed

9. Role of RPA Proteins in Radiation Repair and Recovery

By Patrick E. Gygli, J. Scott Lockhart and Linda C. DeVeaux


Open access peer-reviewed

10. Recognition and Repair Pathways of Damaged DNA in Higher Plants

By Sascha Biedermann, Sutton Mooney and Hanjo Hellmann


Open access peer-reviewed

11. DNA Damage Protection and Induction of Repair by Dietary Phytochemicals and Cancer Prevention: What Do We Know?

By Alice A. Ramos, Cristóvão F. Lima and Cristina Pereira-Wilson


Open access peer-reviewed

12. The Nuclear Compartmentation of Glutathione: Effect on Cell Cycle Progression

By Jelena Markovic, Nancy Mora, Amparo Gimeno, Consuelo Burguete, José Luis García-Gimenez and Federico V. Pallardó


Open access peer-reviewed

13. Role for PKCδ on Apoptosis in the DNA Damage Response

By Kiyotsugu Yoshida


Open access peer-reviewed

14. New Players in Recognition of Intact and Cleaved AP Sites: Implication in DNA Repair in Mammalian Cells

By Svetlana Khodyreva and Olga Lavrik


Open access peer-reviewed

15. SiDNA and Other Tools for the Indirect Induction of DNA Damage Responses

By Maria Quanz, Amélie Croset and Marie Dutreix


Open access peer-reviewed

16. DNA Repair in Pathogenic Eukaryotic Cells: Insights from Comparative Genomics of Parasitic Protozoan

By Laurence A. Marchat, Mavil López-Casamichana, Esther Orozco and César López-Camarillo


Open access peer-reviewed

17. Mechanisms of Mutagenic DNA Nucleobase Damages and Their Chemical and Enzymatic Repairs Investigated by Quantum Chemical Methods

By Eric A. C. Bushnell, Jorge Llano, Leif A. Eriksson and James W. Gauld


Open access peer-reviewed

18. DNA Radiosensitization: The Search for Repair Refractive Lesions Including Double Strand Breaks and Interstrand Crosslinks

By Tsvetan G. Gantchev, Marie-Eve Dextraze and Darel J. Hunting


Open access peer-reviewed

19. The Influence of Individual Genome Sensitivity in DNA Damage Repair Assessment in Chronic Professional Exposure to Low Doses of Ionizing Radiation

By Mirta Milić, Ružica Rozgaj, Vilena Kašuba, Ana Marija Jazbec, Patrizia Hrelia and Sabrina Angelini


Open access peer-reviewed

20. Application of Host Cell Reactivation in Evaluating the Effects of Anticancer Drugs and Environmental Toxicants on Cellular DNA Repair Activity in Head and Neck Cancer

By Yi-Shan Tsai, Jau-Ling Huang and Chang-Shen Lin


Open access peer-reviewed

21. Role of Radioprotectors in the Inhibition of DNA Damage and Modulation of DNA Repair After Exposure to Gamma-Radiation

By Dharmendra Kumar Maurya and Thomas Paul Asir Devasagayam


Open access peer-reviewed

22. DNA-Binding Radioprotectors

By Pavel Lobachevsky, Alesia Ivashkevich, Olga A. Martin and Roger F. Martin


Open access peer-reviewed

23. DNA Damage Response and Repair: Insights into Strategies for Radiation Sensitization

By Joshua D. Lawson, Kristopher T. Kahle, Kimberly Ng, Bob Carter, Santosh Kesari and Clark C. Chen


Open access peer-reviewed

24. The Botanical Extract Feverfew PFE Reduces DNA Damage and Induces DNA Repair Processes

By Michael D. Southall, Simarna Kaur and Khalid Mahmood


Open access peer-reviewed

25. Food Factors and Oxidative DNA Damage / DNA Repair Systems

By Takeshi Hirano and Kazuyoshi Tamae


Open access peer-reviewed

26. Enhancing DNA Repair by Combining only Dietary Supplement Ingredients that do not Metabolically Compete in Order to Achieve Synergism

By Ronald W. Pero


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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