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Open access peer-reviewed Edited Volume

Plasmodium Species and Drug Resistance

Edited by Rajeev K. Tyagi

CSIR-Institute of Microbial Technology (IMTECH)

As teachers of parasite biology, we are becoming increasingly aware of the lack of detailed information and experimental approaches about drugs and drug resistance in many medical schools and undergraduate courses. Therefore, this book discusses parasite biology, antimalarial drugs and their mechanism of action, and the dynamic situation of evolving drug resistance of parasites, which has become a pressing issue. It provides insight into the plasmodium species, the role of cytokines in activating immune response during malaria infection, the importance of antimalarials as a therapeutic option, issues of drug resistance and co-resistance, and validation of evolved resistance in humanized mouse models. It is a timely addition to the existing literature on malaria parasite biology and a useful resource for students, researchers, and those working in the field of parasite biology, drugs, drug resistance of infectious diseases in general, and human malaria parasites in particular and beyond.

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Plasmodium Species and Drug ResistanceEdited by Rajeev K. Tyagi

Published: November 10th 2021

DOI: 10.5772/intechopen.91077

ISBN: 978-1-83969-256-7

Print ISBN: 978-1-83969-255-0

eBook (PDF) ISBN: 978-1-83969-257-4

Copyright year: 2021

Books open for chapter submissions

1234 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Finding Novel Strategies to Overcome the Impact of Malaria Vector Resistance in Limited-Resources Settings. The Case of Cameroon as a Basis for Reflection

By Benjamin Jr Fouda Abougou

44

Open access peer-reviewed

2. Plasmodium Species and Drug Resistance

By Sintayehu Tsegaye Tseha

81

Open access peer-reviewed

3. Recent Advances in Antimalarial Drug Discovery: Challenges and Opportunities

By Imrat, Ajeet Kumar Verma and Pooja Rani Mina

91

Open access peer-reviewed

4. Adaptive Drug Resistance in Malaria Parasite: A Threat to Malaria Elimination Agenda?

By Moses Okpeku

103

Open access peer-reviewed

5. Treatment of Malaria Infection and Drug Resistance

By Bernard Kofi Turkson, Alfred Ofori Agyemang, Desmond Nkrumah, Reinhard Isaac Nketia, Michael Frimpong Baidoo and Merlin Lincoln Kwao Mensah

111

Open access peer-reviewed

6. P. falciparum and Its Molecular Markers of Resistance to Antimalarial Drugs

By Peter Hodoameda

94

Open access peer-reviewed

7. A Double Line of Defense: Heat Shock Proteins and Polyamines Act as Contributing Factors to Drug Resistance of some Plasmodium Parasites

By Xolani Henry Makhoba

37

Open access peer-reviewed

8. Molecular Approaches for Malaria Therapy

By Mitali Mishra, Vikash Kumar Mishra, Varsha Kashaw and Sushil Kumar Kashaw

66

Open access peer-reviewed

9. Regulation of T-reg/Th-17 Balance: One Step Closer Towards Immunotherapy Against Malaria Infection

By Saikat Mukherjee, Soubhik Ghosh and Arindam Bhattacharyya

68

Open access peer-reviewed

10. A Comprehensive Review of 4(1H)-Quinolones and 4(1H)-Pyridones for the Development of an Effective Antimalarial

By Ami H. Asakawa and Roman Manetsch

146

Open access peer-reviewed

11. Stable Artesunate Resistance in A Humanized Mouse Model of Plasmodium falciparum

By Sheetal Saini, Rajinder Kumar and Rajeev K. Tyagi

46

Open access peer-reviewed

12. Drug Design for Malaria with Artificial Intelligence (AI)

By Bhaswar Ghosh and Soham Choudhuri

117

Open access peer-reviewed

13. Plasmodium vivax and Drug Resistance

By Puji Budi Setia Asih and Din Syafruddin

117

Open access peer-reviewed

14. rRNA Platform Technology for Drug Discovery Methods for Identifying Ligands That Target Plasmodium RNA Structural Motifs

By Harrison Ndung’u Mwangi and Francis Jackim Mulaa

31

Open access peer-reviewed

15. Malaria: Introductory Concepts, Resistance Issues and Current Medicines

By Dejen Nureye

95

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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