Amalia Stefaniu

National Institute for Chemical - Pharmaceutical Research and Development

Amalia Stefaniu has a background in chemical engineering, acquiring her Bachelor’s degree at Politehnica University of Bucharest, Faculty of Engineering in Foreign Languages. She followed postgraduate academic studies with Drugs and Cosmetics specialization and she obtained a Masters degree in Biotechnologies and food safety. She completed her PhD in Exact Sciences - Chemistry Domain in 2011 at the University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Inorganic Chemistry, Physical Chemistry and Electrochemistry. She joined the National Institute for Chemical Pharmaceutical Research and Development, Bucharest in 2001, where she worked first as Chemical Research Engineer in the Pharmaceutical Biotechnologies domain. Her current position is Senior Research Scientist. Her research focuses on properties prediction, mathematical modeling, molecular docking, and therapeutic compounds design.

2books edited

5chapters authored

Latest work with IntechOpen by Amalia Stefaniu

Cheminformatics has emerged as an applied branch of Chemistry that involves multidisciplinary knowledge, connecting related fields such as chemistry, computer science, biology, pharmacology, physics, and mathematical statistics.The book is organized in two sections, including multiple aspects related to advances in the development of informatic tools and their specific use in compound structure databases with various applications in life sciences, mainly in medicinal chemistry, for identification and development of new therapeutically active molecules. The book covers aspects related to genomic analysis, semantic similarity, chemometrics, pattern recognition techniques, chemical reactivity prediction, drug-likeness assessment, bioavailability, biological target recognition, machine-based drug discovery and design. Results from various computational tools and methods are discussed in the context of new compound design and development, sharing promising opportunities, and perspectives.

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