Open access peer-reviewed Edited volume

Cystic Fibrosis

Renewed Hopes Through Research

Living healthy is all one wants, but the genetics behind creation of every human is different. As a curse or human agony, some are born with congenital defects in their menu of the genome. Just one has to live with that! The complexity of cystic fibrosis condition, which is rather a slow-killer, affects various organ systems of the human body complicating further with secondary infections. That's what makes the disease so puzzling for which scientists around the world are trying to understand better and to find a cure. Though they narrowed down to a single target gene, the tentacles of the disease reach many unknown corners of the human body. Decades of scientific research in the field of chronic illnesses like this one surely increased the level of life expectancy. This book is the compilation of interesting chapters contributed by eminent interdisciplinary scientists around the world trying to make the life of cystic fibrosis patients better.

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Cystic FibrosisRenewed Hopes Through ResearchEdited by Dinesh Sriramulu

Published: March 28th 2012

DOI: 10.5772/1463

ISBN: 978-953-51-0287-8

Copyright year: 2012

Books open for chapter submissions

61836 Total Chapter Downloads

7 Crossref Citations

23 Web of Science Citations

27 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. The Prognosis of Cystic Fibrosis - A Clinician's Perspective

By Patrick Lebecque

7242

Open access peer-reviewed

2. Radiological Features of Cystic Fibrosis

By Iara Maria Sequeiros and Nabil A. Jarad

5906

Open access peer-reviewed

3. The Cystic Fibrosis 'Gender Gap': Past Observations Present Understanding and Future Directions

By Sanjay H. Chotirmall, Catherine M. Greene, Brian J. Harvey and Noel G. McElvaney

1695

Open access peer-reviewed

4. Cystic Fibrosis and Infertility

By Maria do Carmo Pimentel Batitucci, Angela Maria Spagnol Perrone and Giselle Villa Flor Brunoro

1671

Open access peer-reviewed

5. The Genetics of CFTR: Genotype - Phenotype Relationship, Diagnostic Challenge and Therapeutic Implications

By Marco Lucarelli, Silvia Pierandrei, Sabina Maria Bruno and Roberto Strom

2262

Open access peer-reviewed

6. Biochemical and Molecular Genetic Testing Used in the Diagnosis and Assessment of Cystic Fibrosis

By Donovan McGrowder

3203

Open access peer-reviewed

7. Pseudomonas aeruginosa Biofilm Formation in the CF Lung and Its Implications for Therapy

By Gregory G. Anderson

2891

Open access peer-reviewed

8. Outcome and Prevention of Pseudomonas aeruginosa-Staphylococcus aureus Interactions During Pulmonary Infections in Cystic Fibrosis

By Gabriel Mitchell and François Malouin

1436

Open access peer-reviewed

9. Infection by Non Tuberculous Mycobacteria in Cystic Fibrosis

By María Santos, Ana Gil-Brusola and Pilar Morales

2526

Open access peer-reviewed

10. Atypical Bacteria in the CF Airways: Diversity, Clinical Consequences, Emergence and Adaptation

By Marchandin Hélène, Michon Anne-Laure and Jumas-Bilak Estelle

2343

Open access peer-reviewed

11. Viral Respiratory Tract Infections in Cystic Fibrosis

By Dennis Wat

2364

Open access peer-reviewed

12. Immune Dysfunction in Cystic Fibrosis

By Yaqin Xu and Stefan Worgall

2290

Open access peer-reviewed

13. Channel Replacement Therapy for Cystic Fibrosis

By John M. Tomich, Urška Bukovnik, Jammie Layman and Bruce D. Schultz

1540

Open access peer-reviewed

14. Improving Cell Surface Functional Expression of Delta F508 CFTR: A Quest for Therapeutic Targets

By Yifei Fan, Yeshavanth K. Banasavadi-Siddegowda and Xiaodong Wang

2167

Open access peer-reviewed

15. Fine Tuning of CFTR Traffic and Function by PDZ Scaffolding Proteins

By Florian Bossard, Emilie Silantieff and Chantal Gauthier

1259

Open access peer-reviewed

16. CFTR Gene Transfer and Tracking the CFTR Protein in the Airway Epithelium

By Gaëlle Gonzalez, Pierre Boulanger and Saw-See Hong

2125

Open access peer-reviewed

17. VIP as a Corrector of CFTR Trafficking and Membrane Stability

By Valerie Chappe and Sami I. Said

1650

Open access peer-reviewed

18. Pharmacological Potential of PDE5 Inhibitors for the Treatment of Cystic Fibrosis

By Bob Lubamba, Barbara Dhooghe, Sabrina Noël and Teresinha Leal

2725

Open access peer-reviewed

19. Pharmacological Modulators of Sphingolipid Metabolism for the Treatment of Cystic Fibrosis Lung Inflammation

By M.C. Dechecchi, E. Nicolis, P. Mazzi, M. Paroni, F. Cioffi, A. Tamanini,V. Bezzerri, M. Tebon, I. Lampronti, S. Huang, L. Wiszniewski, M.T. Scupoli, A. Bragonzi, R. Gambari, G. Berton and G. Cabrini

1335

Open access peer-reviewed

20. The Importance of Adherence and Compliance with Treatment in Cystic Fibrosis

By Rosa Patricia Arias-Llorente, Carlos Bousoño García and Juan J. Díaz Martín

3501

Open access peer-reviewed

21. Improving the Likelihood of Success in Trials and the Efficiency of Delivery of Mucolytics and Antibiotics

By Carlos F. Lange

1093

Open access peer-reviewed

22. Airways Clearance Techniques in Cystic Fibrosis: Physiology, Devices and the Future

By Adrian H. Kendrick

3610

Open access peer-reviewed

23. The Physiotherapist's Use of Exercise in the Management of Young People with Cystic Fibrosis

By Allison Mandrusiak and Pauline Watter

2642

Open access peer-reviewed

24. Exercise Performance and Breathing Patterns in Cystic Fibrosis

By Georgia Perpati

2360

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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