Open access peer-reviewed Edited Volume

Progress in Understanding Cystic Fibrosis

Congenital defects in humans are of greater concern, and in that line, cystic fibrosis (CF) has been one of the most complex diseases posing treatment challenge till date. Though it is a chronic condition, CF is closely associated with dysfunction of various organ systems of the human body, which in turn results in secondary infections by microbes. Decades of research by scientists worldwide has narrowed down the cause of CF to a single target gene. But the complexity of the disease is the prime impediment to finding a single-shot cure. Fortunately, the multidisciplinary approach toward understanding and management of the CF condition has certainly increased the level of life expectancy among CF patients. In particular, the "omics" and the "systems biology" approach have greatly widened the focal area for better understanding of the disease. This book includes a collection of interesting chapters contributed by eminent scientists around the world who have been striving to improve the life of those affected by CF.

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Progress in Understanding Cystic FibrosisEdited by Dinesh Sriramulu

Published: July 12th 2017

DOI: 10.5772/63263

ISBN: 978-953-51-3292-9

Print ISBN: 978-953-51-3291-2

eBook (PDF) ISBN: 978-953-51-4736-7

Copyright year: 2017

Books open for chapter submissions

7534 Total Chapter Downloads

7 Crossref Citations

5 Web of Science Citations

13 Dimensions Citations


Open access peer-reviewed

1. CFTR Involvement in Cell Migration and Epithelial Restitution

By Scott M. O'Grady


Open access peer-reviewed

2. Cystic Fibrosis–Related Diabetes

By Bernadette Prentice, Shihab Hameed, Chee Y. Ooi, Charles F. Verge and John Widger


Open access peer-reviewed

3. The Cystic Fibrosis Airway Microbiome and Pathogens

By Ibrahim A. Janahi and Abdul Rehman


Open access peer-reviewed

4. Burkholderia cepacia Complex Infections Among Cystic Fibrosis Patients: Perspectives and Challenges

By Jorge H. Leitão, Joana R. Feliciano, Sílvia A. Sousa, Tiago Pita and Soraia I. Guerreiro


Open access peer-reviewed

5. Pseudomonas aeruginosa Extracellular Secreted Molecules Have a Dominant Role in Biofilm Development and Bacterial Virulence in Cystic Fibrosis Lung Infections

By Theerthankar Das and Jim Manos


Open access peer-reviewed

6. Structure‐Function Relationships of Rhamnolipid and Exopolysacharide Biosurfactants of Pseudomonas aeruginosa as Therapeutic Targets in Cystic Fibrosis Lung Infections

By Milena G. Rikalovic, Natasa S. Avramovic and Ivanka M. Karadzic


Open access peer-reviewed

7. Anti‐PcrV Immunization for Pseudomonas aeruginosa Pneumonia in Cystic Fibrosis

By Yoshifumi Naito, Kiyoshi Moriyama and Teiji Sawa


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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