Open access peer-reviewed Edited Volume

Pulmonary Hypertension

From Bench Research to Clinical Challenges

Edited by Roxana Sulica

Yeshiva University, United States of America


Ioana Preston

Tufts Medical Center, United States of America

The textbook "Pulmonary Hypertension - From Bench Research to Clinical Challenges" addresses the following topics: structure and function of the normal pulmonary vasculature; disregulated cellular pathways seen in experimental and human pulmonary hypertension; clinical aspects of pulmonary hypertension in general; presentation of several specific forms of pulmonary hypertension, and management of pulmonary hypertension in special circumstances. The textbook is unique in that it combines pulmonary and cardiac physiology and pathophysiology with clinical aspects of the disease. First two sections are reserved for the basic knowledge and the recent discoveries related to structure and cellular function of the pulmonary vasculature. The chapters also describe disregulated pathways known to be affected in pulmonary hypertension. A special section deals with the effects of hypoxia on the pulmonary vasculature and the myocardium. Other three sections introduce the methods of evaluating pulmonary hypertension to the reader. The chapters present several forms of pulmonary hypertension which are particularly challenging in clinical practice (such as pulmonary arterial hypertension associated with systemic sclerosis), and lastly, they address special considerations regarding management of pulmonary hypertension in certain clinical scenarios such as pulmonary hypertension in the critically ill.

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Pulmonary HypertensionFrom Bench Research to Clinical ChallengesEdited by Roxana Sulica

Published: December 9th 2011

DOI: 10.5772/1291

ISBN: 978-953-307-835-9

eBook (PDF) ISBN: 978-953-51-6710-5

Copyright year: 2011

Books open for chapter submissions

56933 Total Chapter Downloads

4 Crossref Citations

13 Web of Science Citations

17 Dimensions Citations


Open access peer-reviewed

1. Pulmonary Hypertension: Endothelial Cell Function

By Rajamma Mathew


Open access peer-reviewed

2. Integrin-Mediated Endothelial Cell Adhesion and Activation of c-Src, EGFR and ErbB2 are Required for Endothelial-Mesenchymal Transition

By Enrique Arciniegas, Luz Marina Carrillo, Héctor Rojas and José Cardier


Open access peer-reviewed

3. Interplay Between Serotonin Transporter Signaling and Voltage-Gated Potassium Channel (Kv) 1.5 Expression

By Christophe Guignabert


Open access peer-reviewed

4. Deregulation of BMP Signaling in the Pathogenesis of Pulmonary Hypertension

By Miriam de Boeck and Peter ten Dijke


Open access peer-reviewed

5. ω3 and ω6 CYP450 Eicosanoid Derivatives: Key Lipid Mediators in the Regulation of Pulmonary Hypertension

By Caroline Morin, Samuel Fortin, Christelle Guibert and Éric Rousseau


Open access peer-reviewed

6. Hypoxic Pulmonary Arterial Hypertension in the Chicken Model

By Aureliano Hernández and Martha de Sandino


Open access peer-reviewed

7. Inadequate Myocardial Oxygen Supply/Demand in Experimental Pulmonary Hypertension

By B. J. van Beek-Harmsen, H. M. Feenstra and W. J. van der Laarse


Open access peer-reviewed

8. Assessment of Structural and Functional Pulmonary Vascular Disease in Patients with PAH

By Juan Grignola, Enric Domingo, Rio Aguilar-Torres and Antonio Roman


Open access peer-reviewed

9. Dyspnea in Pulmonary Arterial Hypertension

By Dimitar Sajkov, Karen Latimer and Nikolai Petrovsky


Open access peer-reviewed

10. Echocardiography in Pulmonary Hypertension

By Chin-Chang Cheng and Chien-Wei Hsu


Open access peer-reviewed

11. Pulmonary Hypertension in Systemic Sclerosis

By Muhammad Ishaq Ghauri, Jibran Sualeh Muhammad and Kamran Hameed


Open access peer-reviewed

12. Clinical Syndromes and Associations with Persistent Pulmonary Hypertension of the Newborn

By Jae H. Kim and Anup Katheria


Open access peer-reviewed

13. Sarcoidosis Associated Pulmonary Hypertension

By Veronica Palmero, Phillip Factor and Roxana Sulica


Open access peer-reviewed

14. Pulmonary Hypertension in Patients with Chronic Kidney Disease

By Alessandro Domenici, Remo Luciani, Francesco Principe, Francesco Paneni, Giuseppino Massimo Ciavarella and Luciano De Biase


Open access peer-reviewed

15. Perioperative Management of Pulmonary Hypertension

By Philip L. Kalarickal, Sabrina T. Bent, Michael J. Yarborough, Kavitha A. Mathew and Charles Fox


Open access peer-reviewed

16. Pregnancy and Pulmonary Arterial Hypertension

By Jean M. Elwing and Ralph J. Panos


Open access peer-reviewed

17. Pulmonary Hypertension in the Critically Ill

By Michelle S. Chew, Anders Åneman, John F. Fraser and Anthony S. McLean


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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