Open access peer-reviewed Edited volume

Carcinogenesis

Carcinogenesis covers molecular, biochemical and cellular processes that underpin this field. The complex nature of cancer means that a broad understanding of these processes is advantageous when designing novel preventative, therapeutic or diagnostic strategies. This book commences with chapters discussing cancer predisposition and pre-cancerous lesions. Factors that initiate or progress cancer development, including viral, hormonal, oncogenic and biochemical stimuli are then described, as are interactions with the cancer extracellular environment. Animal models are particularly useful for evaluating therapeutic or chemopreventive agents and examples are presented. Finally, natural products that ether prevent or treat cancer are described. Together these topics will provide the reader with examples of the latest cutting edge research and discoveries, with the goal of stimulating further advances.

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CarcinogenesisEdited by Kathryn Tonissen

Published: January 23rd 2013

DOI: 10.5772/2982

ISBN: 978-953-51-0945-7

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Open access peer-reviewed

1. Synergistic Effects of Low-Risk Variant Alleles in Cancer Predisposition

By Francesca Duraturo, Raffaella Liccardo, Angela Cavallo, Marina De Rosa and Paola Izzo

1281

Open access peer-reviewed

2. Binary System of Grading Epithelial Dysplasia in Oral Leukoplakias

By Maria Auxiliadora Vieira do Carmo and Patrícia Carlos Caldeira

3712

Open access peer-reviewed

3. Human Papillomavirus and Carcinogenesis in the Upper Aero-Digestive Tract

By Andrés Castillo

1793

Open access peer-reviewed

4. Oestrogens, Xenoestrogens and Hormone-Dependent Cancers

By Anna Ptak and Ewa Lucja Gregoraszczuk

1263

Open access peer-reviewed

5. EPS8, an Adaptor Protein Acts as an Oncoprotein in Human Cancer

By Ming-Chei Maa and Tzeng-Horng Leu

1707

Open access peer-reviewed

6. FJ194940.1 Gene and Its Protein Product ACJ04040.1 – Potential Tumor Marker – From Protein to cDNA and Chromosomal Localization

By Ewa Balcerczak, Aleksandra Sałagacka, Malwina Bartczak-Tomczyk and Marek Mirowski

766

Open access peer-reviewed

7. The Interaction Between Redox and Hypoxic Signalling Pathways in the Dynamic Oxygen Environment of Cancer Cells

By Maneet Bhatia, Therese C. Karlenius, Giovanna Di Trapani and Kathryn F. Tonissen

21910

Open access peer-reviewed

8. Expressional Alterations of Versican, Hyaluronan and Microfibril Associated Proteins in the Cancer Microenvironment

By Hiroko Kuwabara, Masahiko Yoneda and Zenzo Isogai

1103

Open access peer-reviewed

9. Molecular Mechanisms of Metastasis: Epithelial-Mesenchymal Transition, Anoikis and Loss of Adhesion

By M.E. Hernández-Caballero

12147

Open access peer-reviewed

10. Lobe-Specific Carcinogenesis in the Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mouse Model

By Jinhui Zhang, Lei Wang, Yong Zhang and Junxuan Lu

914

Open access peer-reviewed

11. Mechanism of Urinary Bladder Carcinogenesis Induced by a Xanthine Oxidoreductase Inhibitor, in Rats

By Naoki Naoki Ashizawa and Takeo Shimo

1258

Open access peer-reviewed

12. Cancer Chemoprevention by Dietary Polyphenols

By Magdy Sayed Aly and Amani Abd ElHamid Mahmoud

1941

Open access peer-reviewed

13. Kuguacin J, a Triterpenoid from Momordica charantia Linn: A Comprehensive Review of Anticarcinogenic Properties

By Pornngarm Limtrakul, Pornsiri Pitchakarn and Shugo Suzuki

12114

Open access peer-reviewed

14. Regulation of Apoptosis, Invasion and Angiogenesis of Tumor Cells by Caffeic Acid Phenethyl Ester

By Mohamed F. El-Refaei and Essam A. Mady

1351

Edited volume and chapters are indexed in

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  • AZ ebsco
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  • CNKI

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23260total chapter downloads

10Web of Science citations

4Crossref citations

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