Open access peer-reviewed Edited Volume

Tumor Microenvironment and Myelomonocytic Cells

Tumor microenvironment represents an extremely dynamic niche shaped by the interplay of different cell types (e.g. tumor cells, stromal cells), their soluble products (e.g.cytokines, chemokines and growth factors) and varied physico-chemical conditions (e.g low oxygen concentration or hypoxia). Recent studies have identified myelomonocytic cells as key players in regulating the tumor microenvironment and hence, tumor progression in a variety of cancers. In view of these findings, the present book attemps to provide a comprehensive account of the diversity of tumor microenvironment across different cancers and how myelomonocytic cells have taken the center-stage in regulating this niche to direct cancer progression. A better understanding of the myelomonocytic cells and the mechanisms by which they regulate cancer progression will open new vistas in cancer therapeutics.

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Tumor Microenvironment and Myelomonocytic CellsEdited by Subhra Biswas

Published: March 30th 2012

DOI: 10.5772/1507

ISBN: 978-953-51-0439-1

eBook (PDF) ISBN: 978-953-51-6946-8

Copyright year: 2012

Books open for chapter submissions

35712 Total Chapter Downloads

11 Crossref Citations

20 Web of Science Citations

28 Dimensions Citations


Open access peer-reviewed

1. Cell Lineage Commitment and Tumor Microenvironment as Determinants for Tumor-Associated Myelomonocytic Cells Plasticity

By Raffaella Bonecchi1, Benedetta Savino1, Matthieu Pesant1 and Massimo Locati1


Open access peer-reviewed

2. Functions of Diverse Myeloid Cells in the Tumor Micro-Environment

By Paola Allavena and Antonio Sica


Open access peer-reviewed

3. Monocyte Subsets and Their Role in Tumor Progression

By Andrea Doseff and Arti Parihar


Open access peer-reviewed

4. Myeloid Derived Suppressor Cells: Subsets, Expansion, and Role in Cancer Progression

By Jean-Pierre Abastado and Liang Zhi


Open access peer-reviewed

5. The Role of Hypoxia in Re-educating Macrophages in the Tumour Environment

By Reuben J. Harwood1, Claire E. Lewis and Subhra K. Biswas


Open access peer-reviewed

6. Tumor Inflammatory Microenvironment in EMT and Metastasis

By Tingting Yuan, Yadi Wu and Peter Zhou


Open access peer-reviewed

7. Lung Tumor Microenvironment and Myelomonocytic Cells

By Minu Srivastava, Asa Andersson, Li Zhu, Marni Harris-White, Jay M Lee, Steven Dubinett and Sherven Sharma


Open access peer-reviewed

8. Immunobiology of Monocytes/Macrophages in Hepatocellular Carcinoma

By Dong-Ming Kuang and Limin Zheng


Open access peer-reviewed

9. Macrophages and Microglia in Brain Malignancies

By Cristina Riccadonna and Paul R Walker


Open access peer-reviewed

10. The Role of Tumor Microenvironment in Oral Cancer

By Masakatsu Fukuda, Yoshihiro Ohmori and Hideaki Sakashita


Open access peer-reviewed

11. Modulation of Cancer Progression by Tumor Microenvironmental Leukocyte-Expressed microRNAs

By Lorenzo Sempere and Jose Conejo-Garcia


Open access peer-reviewed

12. The Role of Mesenchymal Stem Cells in the Tumor Microenvironment

By Aline M. Betancourt and Ruth S. Waterman


Open access peer-reviewed

13. Visualization of Myelomonocytic Cells in Tumours

By Tatyana Chtanova and Lai Guan Ng


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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