Open access peer-reviewed Edited Volume

Hepatitis C

From Infection to Cure

Edited by Imran Shahid

Umm al-Qura University

The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis C virus infection progression, as well as other hepatitis C-associated clinical implications. Hepatitis C - From Infection to Cure also provides up-to-date information about hepatitis C cures for clinicians, physicians, and healthcare providers with an ample understanding of the current treatment horizon, as well as other investigational and emerging treatment strategies. The authors with their valuable scientific contributions belong to many eminent institutes around the world and are much experienced in hepatitis C virology, pathology, and therapeutics.

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Hepatitis CFrom Infection to CureEdited by Imran Shahid

Published: October 10th 2018

DOI: 10.5772/intechopen.72268

ISBN: 978-1-78984-208-1

Print ISBN: 978-1-78984-207-4

eBook (PDF) ISBN: 978-1-83881-670-4

Copyright year: 2018

Books open for chapter submissions

8890 Total Chapter Downloads

6 Crossref Citations

4 Web of Science Citations

8 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Current and Emerging Anti-Hepatitis C Regimens: Hope or Hype

By Imran Shahid


Open access peer-reviewed

2. Hepatitis C Virus and Inflammation

By Binod Kumar, Akshaya Ramachandran and Gulam Waris


Open access peer-reviewed

3. HCV Lymphotropism and Its Pathogenic Significance

By Tomasz I. Michalak


Open access peer-reviewed

4. The Molecular Background Associated with the Progression of Hepatitis C to Hepatocellular Carcinoma

By Abdel-Rahman N. Zekri, Abeer A. Bahnassy and Mona S. Abdellateif


Open access peer-reviewed

5. Micro-RNA in Hepatocellular Carcinoma - Related Hepatitis C Virus Patients in Correlation to Disease Progression

By Moustafa Nouh Elemeery


Open access peer-reviewed

6. Metabolic Factors and Their Influence on the Clinical Course and Response to HCV Treatment

By Livia M Villar, Cristiane A Villela-Nogueira, Allan P da Silva and Letícia P Scalioni


Open access peer-reviewed

7. Periodontal Implications of Hepatitis C Infection

By Petra Surlin, Dorin Nicolae Gheorghe, Liliana Foia, Amelia Surdu, Vasilica Toma, Sorina Mihaela Solomon, Dan Nicolae Florescu and Ion Rogoveanu


Open access peer-reviewed

8. Hepatitis C: Host and Viral Factors Associated with Response to Therapy and Progression of Liver Fibrosis

By Snezana Jovanovic-Cupic, Ana Bozovic, Milena Krajnovic and Nina Petrovic


Open access peer-reviewed

9. Safety, Tolerability, and Associated Side Effects of Direct- Acting Antivirals

By Sidra Rehman


Open access peer-reviewed

10. Hepatitis C Viral Dynamics Using a Combination Therapy of Interferon, Ribavirin, and Telaprevir: Mathematical Modeling and Model Validation

By Philip Aston, Katie Cranfield, Haley O’Farrell, Alex Cassenote, Cassia J. Mendes-Correa, Aluisio Segurado, Phuong Hoang, George Lankford and Hien Tran


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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