Imran Shahid

Umm Al-Qura University, Makkah, Saudi Arabia

Dr. Imran Shahid is an associate professor in the Department of Pharmacology and Toxicology, Faculty of Medicine, at the Umm Al-Qura University (UQU), Makkah, Saudi Arabia. He earned his bachelor's in Pharmacy (B.Pharm) and Science (B.Sc.) with distinction (Gold Medalist) from the Islamia University of Bahawalpur, Bahawalpur, Pakistan. He received his Ph.D. in Molecular Biology from the University of Punjab, Lahore, Pakistan, which was focused on developing anti-mRNA-based treatment strategies against Hepatitis C Virus Genotype (GT) 1a infection in Pakistan. Based on his significant and creative contributions to research, he was recruited as a faculty to the Department of Pharmacology and Toxicology, College of Pharmacy, UQU, Makkah, Saudi Arabia, in 2012. Herein, He served as a lecturer and an assistant professor for 3 and 5 years, respectively, while actively involved in academics and research projects for the Bachelor of Pharmacy (B.Pharm) and Doctor of Pharmacy (Pharm.D) degree programs. He also profoundly utilized his research skills in two national research projects on HCV molecular pathogenesis, HCV GT-1 & 4 genome variations in the Saudi population (13-MED-944, NSTIP, KACST), and breast and/or colon cancer treatment (13-MED-782, NSTIP, KACST) targeting multi-tyrosine kinase pathways by novel agents. The research projects were approved by the American Association for the Advancement of Sciences (AAAS) and Funded by the National Science Technology and Innovation Plan (NSTIP), King Abdullah City for Science and Technology (KACST), Riyadh, Saudi Arabia. He joined the Department of Pharmacology and Toxicology, Faculty of Medicine, UQU, as an assistant Professor in 2020. He was promoted to Associate Professor of Molecular Biology in 2023 after admitting his fantabulous academic performance and excellent contribution to research in the Faculty of Medicine, UQU, Makkah, Saudi Arabia. He is actively engaged as a course demonstrator in various subjects for the students of the Bachelor of Medicine & Bachelor of Surgery (MBBS) degree program and supervisor of the master students' research program. His specific research focus lies in mapping host-virus networks in HCV disease progression: target identification for therapeutic intervention, Natural phenotypic diversity of HCV NS3/4A protease, NS5A, and NS5B polymerase, molecular basis of virus infectious diseases progression, anti-mRNA based treatment strategies against viral infections, computer-aided drug discovery, development of novel therapeutic strategies and drug delivery methods for breast and/or colon cancer, and hepatocellular carcinoma (HCC) treatment. Currently, his research work on novel therapeutic strategies against Dengue Virus (DENV) infection, functionalized nanoparticle formulations against colon cancer, HCC, and the therapeutic potential of various phytochemicals against metabolic syndrome in animal models is supported by the Deanship of Scientific Research (DSR), Umm Al-Qura University, Makkah, and Ministry of Education, Saudi Arabia, respectively. Dr. Imran Shahid has published many research and review articles in peer-reviewed international journals and authored/edited two books on HCV-host interactions, molecular pathogenesis, and HCV treatment. He is also an associate editor and an active editorial board member of several international journals.

Imran Shahid

1books edited

5chapters authored

Latest work with IntechOpen by Imran Shahid

The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis C virus infection progression, as well as other hepatitis C-associated clinical implications. Hepatitis C - From Infection to Cure also provides up-to-date information about hepatitis C cures for clinicians, physicians, and healthcare providers with an ample understanding of the current treatment horizon, as well as other investigational and emerging treatment strategies. The authors with their valuable scientific contributions belong to many eminent institutes around the world and are much experienced in hepatitis C virology, pathology, and therapeutics.

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