Open access peer-reviewed Edited Volume

Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

Edited by Ana Colette Maurício

University of Porto, Portugal

Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cells will have a crucial role in regenerative medicine. For this reason, these cells have been tested in several clinical trials and compassive treatments in children and adults, concerning a wide range of pathologies and diseases, for instance, for the treatment of cerebral paralysis. Considering the worldwide availability of UCB and UCT units and the absence of ethical concerns will probably become the best sources for cell-based therapies for hematological and nonhematological pathologies. The UCB will also have a crucial role in neonatology-predictive analysis in the near future.

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Umbilical Cord Blood Banking for Clinical Application and Regenerative MedicineEdited by Ana Colette Maurício

Published: January 11th 2017

DOI: 10.5772/62607

ISBN: 978-953-51-2866-3

Print ISBN: 978-953-51-2865-6

eBook (PDF) ISBN: 978-953-51-7331-1

Copyright year: 2017

Books open for chapter submissions

15585 Total Chapter Downloads

6 Crossref Citations

10 Web of Science Citations

11 Dimensions Citations


Open access peer-reviewed

1. Cord Blood Stem Cell Processing, Banking and Thawing

By Robert Y.K. Chow, Qingyu Li, Christine Chow, Vincent Guo, Tracie Dang, Andrew Rao, Tony Zeng, Delon Te-Lun Chow, Baixiang Wang and Michelle Chow


Open access peer-reviewed

2. Reference Intervals of Platelets, Lymphocytes and Cardiac Biomarkers in Umbilical Cord Blood

By Hanah Kim, Mina Hur, Hee-Won Moon and Salvatore Di Somma


Open access peer-reviewed

3. Future Perspectives in HLA Typing Technologies

By Andreas Giannopoulos and Anastasios G. Kriebardis


Open access peer-reviewed

4. Hypercortisolaemia and Hyperinsulinaemia Interaction and their Impact upon Insulin Resistance/Sensitivity Markers at Birth

By Eva Gesteiro Alejos, Francisco J. Sánchez-Muniz and Sara Bastida


Open access peer-reviewed

5. Umbilical Cord Blood Cells for Perinatal Brain Injury: The Right Cells at the Right Time?

By Courtney A. McDonald, Margie Castillo-Melendez, Tayla R. Penny, Graham Jenkin and Suzanne L. Miller


Open access peer-reviewed

6. Umbilical Cord Blood Hematopoietic Stem and Progenitor Cell Expansion for Therapeutic Use

By Suzanne M Watt and Peng Hua


Open access peer-reviewed

7. Umbilical Cord Blood-Derived Therapies as a Treatment for Graft-Versus-Host Disease

By Richard Duggleby, Steve Cox, J Alejandro Madrigal and Aurore Saudemont


Open access peer-reviewed

8. Optimization of Unrelated Donor Cord Blood Transplantation for Thalassemia: Implications for Other Non‐Malignant Indications such as HIV Infection or Autoimmune Diseases

By Christine Chow, Tracie Dang, Vincent Guo, Michelle Chow, Qingyu Li, Delon Te‐Lun Chow, Elizabeth Rao, Tony Zeng, Baixiang Wang and Robert Chow


Open access peer-reviewed

9. Myoblast Differentiation of Umbilical Cord Blood Derived Stem Cells on Biocompatible Composites Scaffold Meshes

By Biswadeep Chaudhuri


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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