Open access peer-reviewed Edited Volume

Major Depressive Disorder

Cognitive and Neurobiological Mechanisms

Edited by Yong-Ku Kim

Korea University, Korea, South

Major depressive disorder (MDD) is a complex and heterogeneous disorder, phenotypically and biologically. MDD may be caused by complex interaction between genes and environment in susceptible individuals. Thus, a combination of certain genetic polymorphism, environmental stress, and personal susceptibility ultimately may induce MDD. Gene-environment interactions in the pathophysiology of MDD lead to advancement in personalized medicine by means of genotyping for inter-individual variability in drug action and metabolism. Gene-environment interactions may explain why some subjects become depressed while others remain unaffected. The aim of this book is to describe current knowledge of MDD from the point of view of neurobiology, molecular genetics and cognition. The authors address a deep understanding of cognitive and neurobiological mechanisms involved in MDD.

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Major Depressive DisorderCognitive and Neurobiological MechanismsEdited by Yong-Ku Kim

Published: June 11th 2015

DOI: 10.5772/58711

ISBN: 978-953-51-2129-9

eBook (PDF) ISBN: 978-953-51-7240-6

Copyright year: 2015

Books open for chapter submissions

10143 Total Chapter Downloads

4 Crossref Citations

9 Web of Science Citations

14 Dimensions Citations


Open access peer-reviewed

1. Different Mechanisms Between Melancholic and Atypical Depression

By Hwa-Young Lee and Yong-Ku Kim


Open access peer-reviewed

2. Neurotrophic Factors and Major Depressive Disorder

By Xiaobin Zhang, Jin Li, Weiwei Sha and Ru Bu


Open access peer-reviewed

3. The Molecular and Quantum Approach to Psychopathology and Consciousness — From Theory to Experimental Practice

By Massimo Cocchi, Lucio Tonello and Fabio Gabrielli


Open access peer-reviewed

4. The Effects of Psychotherapy on Brain Function — Major Depressive Disorder

By Sang Won Jeon and Yong-Ku Kim


Open access peer-reviewed

5. The Neural Mechanism of Negative Cognitive Bias in Major Depression — Theoretical and Empirical Issues

By Zhengzhi Feng, Xiaoxia Wang, Keyu Liu, Xiao Liu, Lifei Wang, Xiao Chen and Qin Dai


Open access peer-reviewed

6. Impaired Mental Processing Speed With Moderate to Severe Symptoms of Depression

By Tabitha W. Payne and Madeline Thompson


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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