Open access peer-reviewed Edited Volume

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Edited by Terry Lichtor

Rush University Medical Center, United States of America

A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

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Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patie...Edited by Terry Lichtor

Published: March 25th 2015

DOI: 10.5772/58501

ISBN: 978-953-51-2031-5

eBook (PDF) ISBN: 978-953-51-7235-2

Copyright year: 2015

Books open for chapter submissions

30053 Total Chapter Downloads

22 Crossref Citations

18 Web of Science Citations

45 Dimensions Citations


Open access peer-reviewed

1. Understanding Mitochondrial DNA in Brain Tumorigenesis

By Abdul Aziz Mohamed Yusoff, Farizan Ahmad, Zamzuri Idris, Hasnan Jaafar and Jafri Malin Abdullah


Open access peer-reviewed

2. Systems Biology of Glioblastoma Multiforme

By Caroline Agha, Hannah C. Machemehl and Hassan M. Fathallah- Shaykh


Open access peer-reviewed

3. Tumor Microenvironment — Perivascular and Perinecrotic Niches

By Davide Schiffer, Marta Mellai, Laura Annovazzi, Cristina Casalone and Paola Cassoni


Open access peer-reviewed

4. Brain Tumor Metabolism — Unraveling Its Role in Finding New Therapeutic Targets

By Vera Miranda Gonçalves, Fátima Baltazar and Rui Manuel Reis


Open access peer-reviewed

5. BMI Transcription Factor as a Novel Target for the Treatment of Brain Tumors

By Mohammad M. Hossain, Bárbara Meléndez, Juan A. Rey, Javier S. Castresana and Mehdi H. Shahi


Open access peer-reviewed

6. Metalloproteinases in Brain Tumors

By Krzysztof Siemianowicz, Wirginia Likus and Jarosław Markowski


Open access peer-reviewed

7. Radiation-Induced Glioma

By Ryuya Yamanaka and Azusa Hayano


Open access peer-reviewed

8. Radiation-Induced Brain Injury After Radiotherapy for Brain Tumor

By Zhihua Yang, Shoumin Bai, Beibei Gu, Shuling Peng, Wang Liao and Jun Liu


Open access peer-reviewed

9. Minimally Invasive but Maximally Effective Treatment of Anterior Skull Based Tumors — The Combination of Advanced Neuroendoscopy and Intraoperative Imaging with iMRI and O-Arm

By Kaveh Asadi-Moghaddam, Joseph C. Taylor and Todd W. Vitaz


Open access peer-reviewed

10. Techniques to Improve the Extent of Brain Tumor Resection — Awake Speech and Motor Mapping, and Intraoperative MRI

By Todd W. Vitaz


Open access peer-reviewed

11. Seizures in Children with Brain Tumours — Epidemiology, Significance, Management, and Outcomes

By Adrianna Ranger and David Diosy


Open access peer-reviewed

12. Treatment of a Brain Tumor Using a DNA-Based Vaccine

By Terry Lichtor


Open access peer-reviewed

13. Imaging of Brain Tumours

By Mike Fay, Chris Bell, Nick Dowson, Simon Puttick and Stephen Rose


Open access peer-reviewed

14. Clinical Trials in Glioblastoma — Designs and Challenges

By Helen Madsen, Justin E. Hellwinkel and Michael W. Graner


Open access peer-reviewed

15. Clinical Presentation of Brain Tumors

By Christie Adams, Joan Sullivan and Todd W. Vitaz


Open access peer-reviewed

16. Immune Modulation by Tumor-Derived Extracellular Vesicles in Glioblastoma

By Justin E. Hellwinkel, Helen Madsen and Michael Graner


Open access peer-reviewed

17. Immunology and Immunotherapy in Brain Tumors — Immune Failure and Potential Counteractions

By Soliman Oushy and Michael W. Graner


Open access peer-reviewed

18. Clinical Effects of Saireito for Patients with Advanced Stage Glioblastoma

By Yasushi Shibata


Open access peer-reviewed

19. Cannabidiol and Cancer — An Overview of the Preclinical Data

By Marta Solinas, Valentina Cinquina and Daniela Parolaro


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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