Open access peer-reviewed Edited Volume

Trends in Cell Signaling Pathways in Neuronal Fate Decision

Edited by Sabine Wislet

University of Liège, Belgium

During the last decades, numerous studies about stem cells and regenerative medicine highlighted new therapeutic approaches to treat several neurological disorders. It is noteworthy that the current optimism over potential stem cell therapies is driven by new understandings of stem cell biology leading to specific cell fate decision. The objectives of this book were: 1) to offer a general understanding of signaling pathways underlying the capacity of differentiation of several types of stem cells into neurons, during the development; 2) to understand how those pathways are altered in pathological conditions; 3) to describe advances in cellular therapy that could be use to restore central nervous system dysfunction in pathological conditions.

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Trends in Cell Signaling Pathways in Neuronal Fate DecisionEdited by Sabine Wislet

Published: March 27th 2013

DOI: 10.5772/3445

ISBN: 978-953-51-1059-0

eBook (PDF) ISBN: 978-953-51-7119-5

Copyright year: 2013

Books open for chapter submissions

33048 Total Chapter Downloads

32 Crossref Citations

46 Web of Science Citations

67 Dimensions Citations


Open access peer-reviewed

1. Role of TGF-β Signaling in Neurogenic Regions After Brain Injury

By Sonia Villapol, Trevor T. Logan and Aviva J. Symes


Open access peer-reviewed

2. Insulin/IGF-Signalling in Embryonic and Adult Neural Proliferation and Differentiation in the Mammalian Central Nervous System

By Tanja Vogel


Open access peer-reviewed

3. The Role of Smad Proteins for Development, Differentiation and Dedifferentiation of Neurons

By Uwe Ueberham and Thomas Arendt


Open access peer-reviewed

4. Wnt Signaling Roles on the Structure and Function of the Central Synapses: Involvement in Alzheimer’s Disease

By Nibaldo C. Inestrosa and Lorena Varela-Nallar


Open access peer-reviewed

5. Roles of Wnt/β-Catenin Signaling in Controlling the Dopaminergic Neuronal Cell Commitment of Midbrain and Therapeutic Application for Parkinson’s Disease

By Liang-Wei Chen


Open access peer-reviewed

6. Regulation of Cell Fate in the Brain by GSK3

By Adam R. Cole


Open access peer-reviewed

7. Neurotrophin Signaling and Alzheimer’s Disease Neurodegeneration − Focus on BDNF/TrkB Signaling

By Jenny Wong


Open access peer-reviewed

8. NFκB Signaling Directs Neuronal Fate Decision

By Yonggang Zhang and Wenhui Hu


Open access peer-reviewed

9. Telencephalic Neurogenesis Versus Telencephalic Differentiation of Pluripotent Stem Cells

By Roxana Nat, Galina Apostolova and Georg Dechant


Open access peer-reviewed

10. Regulation of Basal and Injury-Induced Fate Decisions of Adult Neural Precursor Cells: Focus on SOCS2 and Related Signalling Pathways

By Harleen S. Basrai, Kimberly J. Christie and Ann M. Turnley


Open access peer-reviewed

11. Neural Stem/Progenitor Cells for Spinal Cord Regeneration

By Ryan Salewski, Hamideh Emrani and Michael G. Fehlings


Open access peer-reviewed

12. Epigenetic Regulation of Neural Differentiation from Embryonic Stem Cells

By Atsushi Shimomura and Eri Hashino


Open access peer-reviewed

13. Neural Fate of Mesenchymal Stem Cells and Neural Crest Stem Cells: Which Ways to Get Neurons for Cell Therapy Purpose?

By Virginie Neirinckx, Cécile Coste, Bernard Rogister and Sabine Wislet- Gendebien


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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