Open access peer-reviewed Edited Volume

Antioxidant-Antidiabetic Agents and Human Health

The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.

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Antioxidant-Antidiabetic Agents and Human HealthEdited by Oluwafemi Oguntibeju

Published: February 5th 2014

DOI: 10.5772/57029

ISBN: 978-953-51-1215-0

eBook (PDF) ISBN: 978-953-51-7190-4

Copyright year: 2014

Books open for chapter submissions

50823 Total Chapter Downloads

30 Crossref Citations

61 Web of Science Citations

100 Dimensions Citations


Open access peer-reviewed

1. Lipid Profile, Antidiabetic and Antioxidant Activity of Acacia ataxacantha Bark Extract in Streptozotocin-Induced Diabetic Rats

By Rotimi O. Arise, Aderounmu I. Ganiyu and Oluwafemi O. Oguntibeju


Open access peer-reviewed

2. Oxidative Stress and Diabetic Complications: The Role of Antioxidant Vitamins and Flavonoids

By Omolola R. Ayepola, Nicole L. Brooks and Oluwafemi O. Oguntibeju


Open access peer-reviewed

3. Anti-Diabetic Effects of Nigerian Indigenous Plant Foods/Diets

By Elizabeth A. Udenta, Ikemefuna C. Obizoba and Oluwafemi O. Oguntibeju


Open access peer-reviewed

4. Some Selected Medicinal Plants with Antidiabetic Potentials

By A.A. Oyagbemi, M. Salihu, O.O. Oguntibeju, A.J. Esterhuyse and E.O. Farombi


Open access peer-reviewed

5. The Antidiabetic Activities of the Aqueous Leaf Extract of Phyllanthus Amarus in some Laboratory Animals

By Adeolu Adedapo, Sunday Ofuegbe and Oluwafemi Oguntibeju


Open access peer-reviewed

6. Antidiabetic Botanicals and their Potential Benefits in the Management of Diabetes Mellitus

By Afolabi Clement Akinmoladun, Ebenezer Olatunde Farombi and Oluwafemi Omoniyi Oguntibeju


Open access peer-reviewed

7. Antioxidant-Rich Natural Grain Products and Human Health

By Afam I.O. Jideani, Henry Silungwe, Thakhani Takalani, Tonna A. Anyasi, Henry Udeh and Adewale Omolola


Open access peer-reviewed

8. Nutritional, Therapeutic, and Prophylactic Properties of Vigna subterranea and Moringa oleifera

By Victoria Adaora Jideani and Claudine Florett Diedericks


Open access peer-reviewed

9. Dietary Antioxidant Properties of Vegetable Oils and Nuts – The Race Against Cardiovascular Disease Progression

By Wongama Given Pantsi, Dirk Jacobus Bester, Adriaan Johannes Esterhuyse and Guillaume Aboua


Open access peer-reviewed

10. Plants with Hypolipidaemic Effects from Nigerian Flora

By Ngozi Justina Nwodo, Charles Okeke Nnadi, Akachukwu Ibezim and Chika John Mbah


Open access peer-reviewed

11. Garlic and Its Effects on Health with Special Reference to the Reproductive System

By Carlo Valente, Guillaume Aboua and Stefan S. Du Plessis


Open access peer-reviewed

12. Potentials of Phytotherapeutic Treatment of Erectile Dysfunction

By Guillaume Aboua, Claudine Manirafasha, Boitumelo R. Mosito, Michelle van der Linde and Stefan S. du Plessis


Open access peer-reviewed

13. Buchu – The Multi-Purpose Ethnomedicinally Important Specie and Its Benefits in the Reproductive System

By Bongekile Skosana, Guillaume Aboua and Stefan S du Plessis


Open access peer-reviewed

14. Antioxidant -Rich Natural Products and Diabetes Mellitus

By Ayodeji B. Oyenihi, Nicole L. Brooks, Oluwafemi O. Oguntibeju and Guillaume Aboua


Open access peer-reviewed

15. Potential Role of Parkia biglobosa in the Management and Treatment of Cardiovascular Diseases

By O.B.L. Alinde, A.J. Esterhuyse and O.O. Oguntibeju


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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