Type 1 Diabetes

David Wagner

doi:10.5772/866

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Open access peer-reviewed Edited Volume

Pathogenesis, Genetics and Immunotherapy

Edited by David Wagner

University of Denver, United States of America

This book is a compilation of reviews about the pathogenesis of Type 1 Diabetes. T1D is a classic autoimmune disease. Genetic factors are clearly determinant but cannot explain the rapid, even overwhelming expanse of this disease. Understanding etiology and pathogenesis of this disease is essential. A number of experts in the field have covered a range of topics for consideration that are applicable to researcher and clinician alike. This book provides apt descriptions of cutting edge technologies and applications in the ever going search for treatments and cure for diabetes. Areas including T cell development, innate immune responses, imaging of pancreata, potential viral initiators, etc. are considered.

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Type 1 DiabetesPathogenesis, Genetics and ImmunotherapyEdited by David Wagner

Published: November 25th 2011

DOI: 10.5772/866

ISBN: 978-953-307-362-0

Books open for chapter submissions

49845 Total Chapter Downloads

14 Crossref Citations

9 Web of Science Citations

19 Dimensions Citations

chapters		Downloads
Open access peer-reviewed 1. Autoimmunity and Immunotherapy of Type 1 Diabetes By Mourad Aribi		2083
Open access peer-reviewed 2. Use of Congenic Mouse Strains for Gene Identification in Type 1 Diabetes By Ute Christine Rogner		1271
Open access peer-reviewed 3. Relationship of Type 1 Diabetes with Human Leukocyte Antigen (HLA) Class II Antigens Except for DR3 and DR4 By Masahito Katahira		1650
Open access peer-reviewed 4. The Role of T Cells in Type 1 Diabetes By David Wagner		2926
Open access peer-reviewed 5. Beta-Cell Function and Failure in Type 1 Diabetes By Maria-Luisa Lazo de la Vega-Monroy and Cristina Fernandez-Mejia		5303
Open access peer-reviewed 6. Steady-State Cell Apoptosis and Immune Tolerance - Induction of Tolerance Using Apoptotic Cells in Type 1 Diabetes and Other Immune-Mediated Disorders By Chang-Qing Xia, Kim Campbell, Benjamin Keselowsky and Michael Clare-Salzler		1207
Open access peer-reviewed 7. Innate Immunity in the Recognition of β-Cell Antigens in Type 1 Diabetes By Jixin Zhong, Jun-Fa Xu, Ping Yang, Yi Liang and Cong-Yi Wang		1732
Open access peer-reviewed 8. The Role of Reg Proteins, a Family of Secreted C-Type Lectins, in Islet Regeneration and as Autoantigens in Type 1 Diabetes By Werner Gurr		1489
Open access peer-reviewed 9. Type I Diabetes and the Role of Inflammatory-Related Cellular Signaling By Lloyd Jesse, Kelleher Andrew, Choi Myung and Keslacy Stefan		1203
Open access peer-reviewed 10. Echovirus Epidemics, Autoimmunity, and Type 1 Diabetes By Oscar Diaz-Horta, Luis Sarmiento, Andreina Baj, Eduardo Cabrera-Rode and Antonio Toniolo		1082
Open access peer-reviewed 11. Environmental Triggers of Type 1 Diabetes Mellitus – Mycobacterium Avium Subspecies Paratuberculosis By Coad Thomas Dow and Leonardo A. Sechi		1583
Open access peer-reviewed 12. In Vivo Monitoring of Inflammation and Regulation in Type 1 Diabetes By Mi-Heon Lee, Sonya Liu, Wen-Hui Lee and Chih-Pin Liu		1192
Open access peer-reviewed 13. Imaging the Pancreatic Beta Cell By Ulf Ahlgren and Elena Kostromina		2311
Open access peer-reviewed 14. Present Accomplishments and Future Prospects of Cell-Based Therapies for Type 1 Diabetes Mellitus By Preeti Chhabra, Clark D. Kensinger, Daniel J. Moore and Kenneth L. Brayman		1298
Open access peer-reviewed 15. Peptides and Proteins for Treatment and Suppression of Type 1 Diabetes By Ahmed H. Badawi, Barlas Büyüktimkin, Paul Kiptoo and Teruna J. Siahaan		1071
Open access peer-reviewed 16. Immunotherapy for Type 1 Diabetes – Preclinical and Clinical Trials By Alice Li and Alan Escher		2066
Open access peer-reviewed 17. Type 1 Diabetes Immunotherapy - Successes, Failures and Promises By Brett E. Phillips and Nick Giannoukakis		1264
Open access peer-reviewed 18. Immunotherapy for Type 1 Diabetes - Necessity, Challenges and Unconventional Opportunities By Rachel Gutfreund and Abdel Rahim A. Hamad		1146
Open access peer-reviewed 19. Autoantigen-Specific Immunotherapy By Shuhong Han, William Donelan, Westley Reeves and Li-Jun Yang		1522
Open access peer-reviewed 20. Multi-Component Vaccines for Suppression of Type 1 Diabetes By William H.R. Langridge and Oludare J. Odumosu		1120
Open access peer-reviewed 21. Porcine Islet Xenotransplantation for the Treatment of Type 1 Diabetes By Dana Mihalicz, Ray V. Rajotte and Gina R. Rayat		1983
Open access peer-reviewed 22. Beta Cell Replacement Therapy By Jeffrey A. SoRelle and Bashoo Naziruddin		1964
Open access peer-reviewed 23. Genetics of Type 1 Diabetes By Tatijana Zemunik and Vesna Boraska		2521
Open access peer-reviewed 24. The Genetics of Type 1 Diabetes By Kathleen M. Gillespie		2258
Open access peer-reviewed 25. Comparative Genetic Analysis of Type 1 Diabetes and Inflammatory Bowel Disease By Marina Bakay, Rahul Pandey and Hakon Hakonarson		1848
Open access peer-reviewed 26. Genetics of Type 1 Diabetes By Marie Cerna		984
Open access peer-reviewed 27. Genetic Markers, Serological Auto Antibodies and Prediction of Type 1 Diabetes By Raouia Fakhfakh		2175
Open access peer-reviewed 28. Genetic Determinants of Type 1 Diabetes By Mohamed M. Jahromi		1593

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