Open access peer-reviewed Edited Volume

Non-Alcoholic Fatty Liver Disease

Molecular Bases, Prevention and Treatment

Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment.

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Non-Alcoholic Fatty Liver DiseaseMolecular Bases, Prevention and TreatmentEdited by Rodrigo Valenzuela Baez

Published: March 21st 2018

DOI: 10.5772/68045

ISBN: 978-953-51-3924-9

Print ISBN: 978-953-51-3923-2

eBook (PDF) ISBN: 978-953-51-4029-0

Copyright year: 2018

Books open for chapter submissions

7584 Total Chapter Downloads

5 Crossref Citations

5 Web of Science Citations

10 Dimensions Citations


Open access peer-reviewed

1. Non-alcoholic Fatty Liver Disease: What We Learn from Omics Studies

By Seyma Katrinli, Kamil Ozdil, Gizem Dinler-Doganay and Levent Doganay


Open access peer-reviewed

2. Molecular Basis for Pathogenesis of Steatohepatitis: Contemporary Understanding and New Insights

By Om Parkash and Subha Saeed


Open access peer-reviewed

3. Role of Lipid Droplet Proteins in the Development of NAFLD and Hepatic Insulin Resistance

By Kaori Minehira and Philippe Gual


Open access peer-reviewed

4. Nonalcoholic Fatty Liver Disease: The Future Frontier of Hepatology for South Asia

By Shahinul Alam, Thupten Kelsang Lama, Golam Mustafa, Mahabubul Alam and Nooruddin Ahmad


Open access peer-reviewed

5. Noninvasive Evaluation of Fibrosis and Steatosis in Nonalcoholic Fatty Liver Disease by Elastographic Methods

By Monica Lupsor-Platon


Open access peer-reviewed

6. Management of Nonalcoholic Fatty Liver Disease (NAFLD)

By Monjur Ahmed


Open access peer-reviewed

7. Nutrition and Lifestyle Modifications in the Prevention and Treatment of Non-Alcoholic Fatty Liver Disease

By Kingsley Asare Kwadwo Pereko, Jacob Setorglo, Matilda Steiner- Asiedu and Joyce Bayebanona Maaweh Tiweh


Open access peer-reviewed

8. Caffeine with Links to NAFLD and Accelerated Brain Aging

By Ian James Martins


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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