Non-Alcoholic Fatty Liver Disease - Molecular Bases, Prevention and Treatment

Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation...

Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment.

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Message of recommendationDear Librarian, I would like to recommend the following IntechOpen book to be added to our library catalog: TITLE: 'Non-Alcoholic Fatty Liver Disease - Molecular Bases, Prevention and Treatment' PRINT ISBN: 978-953-51-3923-2 Libraries are offered a 20% discount on retail book prices. For a quote, please contact the IntechOpen Print Sales Department directly at orders@intechopen.com Best regards.

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