Open access peer-reviewed Edited Volume

Medical Complications of Type 2 Diabetes

Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes and genetic influences on endothelial cell dysfunction. Cardiovascular complications occur at a much lower glucose levels, thus a review on the oral glucose tolerance test compared to other methods was included. The medical conditions associated with type 2 diabetes such as pancreatic cancer, sarcopenia and sleep disordered breathing with diabetes were also discussed. The book concludes with several chapters on the treatments for this disease offering us hope in prevention and successful alleviation of the co-morbidities associated with obesity and type 2 diabetes.

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Medical Complications of Type 2 DiabetesEdited by Colleen Croniger

Published: September 12th 2011

DOI: 10.5772/867

ISBN: 978-953-307-363-7

Copyright year: 2011

Books open for chapter submissions

44214 Total Chapter Downloads

5 Crossref Citations

11 Web of Science Citations

16 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Insulin Secretion and Actions

By Sarawut Jitrapakdee and Briony E. Forbes

3253

Open access peer-reviewed

2. The Oral Glucose Tolerance Test: An Old but Irreplaceable Test to Evaluate Glucose Metabolism and Cardiovascular Risk

By Gian Paolo Fra, Ettore Bartoli and Gian Piero Carnevale Schianca

3491

Open access peer-reviewed

3. The Role of Parathyroid Hormone-Related Protein (PTHRP) in the Pathophysiology of Diabetes Mellitus

By Ioannis Legakis

1765

Open access peer-reviewed

4. Impaired Vascular BK Channel Function in Type 2 Diabetes Mellitus

By Tong Lu and Hon-Chi Lee

1738

Open access peer-reviewed

5. Endothelial Progenitor Cell Dysfunction in Diabetes Mellitus Type-2: Focus on Nitric Oxide System

By Saher Hamed

1871

Open access peer-reviewed

6. Glycaemic Control and Protection of the Vasculature from Glucose Toxicity

By Hong Ding and Chris R. Triggle

1327

Open access peer-reviewed

7. Endothelial Dysfunction and Therapeutic Intervention in Type 2 Diabetes

By Fernando Grover Páez

2032

Open access peer-reviewed

8. Using Gene Expression Signatures to Dissect Insulin Resistance Subtypes

By Brad Hayward, Nicky Konstantopoulos and Ken R. Walder

1610

Open access peer-reviewed

9. The Role of Single Nucleotide Polymorphisms of Untranslated Regions (Utrs) in Insulin Resistance Pathogenesis in Patients with Type 2 Diabetes

By Małgorzata Małodobra

1534

Open access peer-reviewed

10. Genetics of Endothelial Damage Associated to Diabetes Mellitus Type 2

By Lorena García, Carlos Wolff, Verónica Araya, Gloria López, Sergio Lobos, Pilar Durruty and Daniela Seelenfreund

1883

Open access peer-reviewed

11. Functional Context Network of T2DM

By Anja Thormann and Axel Rasche

1196

Open access peer-reviewed

12. Sarcopenia, Sarcopenic Obesity and Insulin Resistance

By John A. Batsis and Silvio Buscemi

3657

Open access peer-reviewed

13. Type 2 Diabetes and Pancreatic Cancer – A Possible Reason

By Parviz M Pour

1657

Open access peer-reviewed

14. Pathophysiology in Type 2 Diabetes – Type 2 Diabetes and Sleep-Disordered Breathing/Sleep Apnea – Role of Adipocytokines

By Ken Kishida

1872

Open access peer-reviewed

15. Can Bariatric or Metabolic Surgery Cure Type 2 Diabetes?

By Gustavo P. S. Miguel, Perseu Carvalho, João Luiz Azevedo, Murilo Hosken Júnior, Évelyn Zambrana, Otávio Azevedo and Isaac Abreu

1645

Open access peer-reviewed

16. Nuclear Imaging of Glucose Transport/Metabolism – An Interesting Tool to Screen Insulin Resistance, Refine Diagnosis of Type 2 Diabetes, Understand Disease Mechanisms, and/or Evaluate New Therapies

By P. Perret, M. Henri, L. Slimani, D.Fagret and C. Ghezzi

1448

Open access peer-reviewed

17. Targeting PKA Signaling to Prevent Metabolic Syndrome and Delay Aging

By Linda C Enns and Warren C Ladiges

1601

Open access peer-reviewed

18. Targeting AMPK for Therapeutic Intervention in Type 2 Diabetes

By Mohamed Kodiha and Ursula Stochaj

3804

Open access peer-reviewed

19. Design and Evaluation of a Complex Phytoceutical Formulation for Circulatory Diseases

By J. Olalde, A. Antoshechkin, O. del Castillo, R. Guzmán and F. Améndola

2601

Open access peer-reviewed

20. Effectiveness of Fenugreek for Lowering Hemoglobin (HbA1c) in Patients with Self-Management of Type 2 Diabetes: A Randomized Controlled Trial

By Rashid Ansari and Saiqaa Ansari

4229

Edited Volume and chapters are indexed in

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