Open access peer-reviewed Edited Volume

Chronic Pancreatitis

Edited by David Sutherland

University of Minnesota, United States of America

Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters include studies on amelioration of chronic pancreatitis in rats by bone marrow derived mesenchymal cells; on gene therapy using HSV-Enkephalin to reduce fibrosis, inflammation and pain in a rats; and on pancreatic acinar and island neogenesis according to vascular and matrix dynamics of human and animal tissue. In regard to the clinical aspects, the role of endoscopic ultrasound in detecting the changes of chronic pancreatitis are addressed as well as the endoscopic treatment via duct drainage procedures or stone removal. Finally, the surgical options for chronic pancreatitis (there are well over 20 procedures) are extensively discussed, with a final chapter on total pancreatectomy and islet autotransplant to definitively remove the root cause of the pain with preservation of endocrine function. This book will be valued by basic scientists and clinicians striving to understand the mechanisms of pain in chronic pancreatitis and the treatment options in patients so afflicted.

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Chronic PancreatitisEdited by David Sutherland

Published: February 15th 2012

DOI: 10.5772/1158

ISBN: 978-953-51-0011-9

eBook (PDF) ISBN: 978-953-51-6797-6

Copyright year: 2012

Books open for chapter submissions

15988 Total Chapter Downloads

1 Web of Science Citations

10 Dimensions Citations


Open access peer-reviewed

1. Bone Marrow Derived Mesenchymal Stem Cells Are Recruited into Injured Pancreas and Contribute to Amelioration of the Chronic Pancreatitis in Rats

By Hong Bin Liu


Open access peer-reviewed

2. Gene Therapy Approach: HSV-Enkephalin Reduces Fibrosis, Inflammation, and Pain

By Karin N. Westlund


Open access peer-reviewed

3. Pancreatic Acinar and Island Neogenesis Correlated with Vascular and Matrix Dynamics

By Garofita-Olivia Mateescu, Mihaela Hincu, B. Oprea, Maria Comanescu and Gabriel Cojocaru


Open access peer-reviewed

4. The Role of Endoscopic Ultrasound to Diagnose, Exclude or Stablish the Parenchimal Changes in Chronic Pancreatitis

By José Celso Ardengh and Eder Rios Lima-Filho


Open access peer-reviewed

5. Endoscopic Treatment in Chronic Pancreatitis

By Yue Sun Cheung and Paul Bo-San Lai


Open access peer-reviewed

6. Surgical Options for Chronic Pancreatitis

By Fazl Q. Parray, Mehmood A. Wani and Nazir A. Wani


Open access peer-reviewed

7. Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis

By David E.R. Sutherland, Melena Bellin, Juan J. Blondet, Greg J. Beilman, Ty B. Dunn, Srinath Chinnakotla, Timothy L. Pruett, Martin L. Freeman, A.N. Balamurugan, Barbara Bland, David Radosevich and Bernhard J. Hering


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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