Open access peer-reviewed Edited Volume

Reactive Oxygen Species

Rizwan Ahmad

Imam Abdulrahman Bin Faisal University

A Professor and Research Coordinator at College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia with an interest in free radicals and autoimmunity. Dr. Ahmad held various teaching and research positions and is the author and reviewer of many articles.


Singlet Oxygen Hydroxyl Radical Superoxide Redox Homeostasis Superoxide Dismutase Catalases Glutathione Reductase Inflammation Systemic Autoimmune Diseases Ageing Nanocarriers for Gene Therapy Biomarkers

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About the book

Reactive oxygen species (ROS) is a wonder molecule which on one hand acts in redox homeostasis and on the other causes damage to various tissues leading to degenerative diseases. When molecular oxygen reacts with electrons it gets converted into ROS. ROS comprises various radicals and non-radical such as superoxide, hydrogen peroxide, singlet oxygen, and hydroxyl radical. Peroxynitrite formed by the merger of nitric oxide and superoxide radical is a highly reactive oxidant with tissue-damaging effects. ROS has great significance in biological metabolism and immune regulation. Abnormal metabolism due to various pathological conditions such as neurodegenerative diseases, diabetes, cancer, and ageing leads to the elevation of ROS. An enhanced level of ROS in the defense mechanisms leads to oxidative stress. This phenomenon causes oxidation of proteins, DNA damage, inhibition of enzymes, and programmed cell death. Scientists are working on developing biomarkers for various diseases. Studies on nanocarriers for gene therapy and designer nanoenzymes envisaged the newer approach towards the elevated and decreased ROS levels. This might lead to precise and site-specific drug/gene delivery depending on the responsiveness of ROS.

The book intends to provide the reader with a comprehensive and systematic overview of reactive oxygen species in health and diseases and the state-of-the-art technology for diagnostic and therapeutic interventions.

Publishing process

Book initiated and editor appointed

Date completed: March 23rd 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: April 20th 2021

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Approved chapters written in full and submitted

Deadline for full chapters: June 19th 2021

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: September 7th 2021

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: November 6th 2021

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About the editor

Rizwan Ahmad

Imam Abdulrahman Bin Faisal University

Dr. Rizwan Ahmad is working as University Professor and Research Coordinator at College of Medicine, Imam Abdulrahman bin Faisal University, Saudi Arabia. He obtained his Ph.D. in Biochemistry from Faculty of Medicine, Jawaharlal Nehru Medical College, AMU, Aligarh, India. He was appointed as Associate Professor of Biochemistry, Department of Human Function, Oman Medical College (OMC) - Oman affiliated with West Virginia University, USA in Sept 2010. Dr. Ahmad has worked as Founding Head, at School of Life and Allied Health Sciences and School of Pharmacy at Glocal University, India. He has guided a Ph.D., 34 PG and 3 UG dissertations. He has published several research papers in peer-reviewed journals. The focus of his research has been on Protein and Nucleic Acid modification and their role in Autoimmune Disorders. He has presented over 50 papers in various National and International Conferences. Dr. Ahmad has delivered many lectures on Immunology and chaired scientific sessions at various conferences. He is also a member of various national and international scientific bodies.

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Book chapters authored 3

Books edited 3

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