Xianquan Zhan

Shandong First Medical University

Prof. Xianquan Zhan received his M.D. and Ph.D. training in preventive medicine at the West China University of Medical Sciences during 1989-1999. He received his post-doctoral training in oncology and cancer proteomics at Central South University and the University of Tennessee Health Science Center (UTHSC). He worked at UTHSC and Cleveland Clinic in the USA during 2001-2012 and achieved the rank of Associate Professor at UTHSC. In 2012, he moved to Central South University and Shandong First Medical University as a Professor, and advisor of MS/PhD graduate students and postdoctoral fellows. He is also the Fellow of Royal Society of Medicine, a Fellow of EPMA, a European EPMA National Representative, a Full member of ASCO, an AAAS member, an Editor-In-Chief of IJCDT, Associate Editors of EPMA Journal and BMC Genomics, and Guest Editors of Frontiers in Endocrinology and Mass Spectrometry Reviews. He has published 173 articles, 30 book chapters, and 2 US patents in the field of clinical proteomics and biomarkers. He edited 10 academic books, including “Proteoforms – Concept and Applications in Medical Sciences”, “Molecular Network Study of Pituitary Adenomas”, “Ubiquitin-Proteasome Pathway”, “Metabolomics - Methodology and Applications in Medical Sciences and Life Sciences”, “Cell Culture - Advanced Technology and Applications in Medical and Life Sciences”, “Modifications of Biomolecules”, and “Biomolecular Modifications in Endocrine-Related Cancers”. As the Guest editor, He edited 18 special issues in SCI journals such as Mass Spectrometry Reviews (IF=10.946), Frontiers in Endocrinology (IF=6.055), EPMA Journal (IF=8.836), and Oxidative Medicine and Cellular Longevity (IF=7.310). His main research interest focuses on the studies of cancer proteomics and proteoforms, multi-omics and biomarkers, and the use of modern omics techniques and systems biology for predictive, preventive, and personalized medicine (3PM) and precision medicine (PM) in cancer.

Xianquan Zhan

5books edited

11chapters authored

Latest work with IntechOpen by Xianquan Zhan

Modifications in biomacromolecules (DNA, RNA, and proteins) are important molecular events in different pathophysiological conditions. These modifications include DNA modifications, RNA post-transcriptional modifications, and protein post-translational modifications that regulate the structures and functions of biomacromolecules and even the entire biological system. In addition, they are associated with a wide spectrum of diseases. Biomacromolecular modifications are important factors in creating proteoforms that constitute the end-point structural and functional forms of a gene or protein that can be applied for predictive, preventive, and personalized medicine (PPPM) as well as precision medicine (PM).

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