Irina Vlasova-St. Louis
Irina St. Louis earned her M.D. and Ph.D. degrees from Ural State Medical Academy, Yekaterinburg, Russia. She completed her residency in lab pathology at Russian Medical Academy for Postgraduate Education, Moscow. She joined the Department of Microbiology at the University of Minnesota, as a postdoctoral trainee, followed by fellowships at the University of Minnesota Supercomputing Institute and Lymphoma Research Foundation. Presently, Dr. St. Louis is appointed as an Assistant Professor at the Department of Medicine at the University of Minnesota. Dr. St. Louis conducts discovery research in several key areas including infectious diseases, immunology, and oncology. By integrating specific areas of expertise - genomics, transcriptomics, proteomics, ribonomics, and bioinformatics - Irina’s group is studying normal and pathological conditions at the molecular, cellular, and organismal levels. The basic research in Dr. St. Louis’ laboratory is centered on post-transcriptional gene expression regulation, specifically, through messenger RNA turnover. Her translational research focuses on immune restoration disorders (IRD). Dr. St. Louis is engaged in a number of clinical studies, within the Global Health & International Medicine Program. These studies involve the stratification of AIDS patients, for optimal treatment regimens. The studies also include searches for biomarkers of immune reconstitution inflammatory syndrome (IRIS). Additionally, Dr. St. Louis’ lab collaborates with the Division of Hematology-Oncology and Transplantation, on virus-specific immune reconstitution after various hematopoietic cell transplantation regimens. This collaborative research aims to define the parameters and conditions for favorable post-transplant immune restoration and functional recovery in adult patients.