Breakthroughs in Melanoma Research

Yohei Tanaka

doi:10.5772/795

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Open access peer-reviewed Edited Volume

Breakthroughs in Melanoma Research

Edited by Yohei Tanaka

Melanoma is considered to be one of the most aggressive forms of skin neoplasms. Despite aggressive researches towards finding treatments, no effective therapy exists to inhibit the metastatic spread of malignant melanoma. The 5-year survival rate of metastatic melanoma is still significantly low, and there has been an earnest need to develop more effective therapies with greater anti-melanoma activity. Through the accomplishment of over 100 distinguished and respected researchers from 19 different countries, this book covers a wide range of aspects from various standpoints and issues related to melanoma. These include the biology of melanoma, pigmentations, pathways, receptors and diagnosis, and the latest treatments and therapies to make potential new therapies. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in melanoma research.

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Breakthroughs in Melanoma ResearchEdited by Yohei Tanaka

Published: November 14th 2011

DOI: 10.5772/795

ISBN: 978-953-307-291-3

eBook (PDF) ISBN: 978-953-51-6564-4

Books open for chapter submissions

56172 Total Chapter Downloads

23 Crossref Citations

33 Web of Science Citations

45 Dimensions Citations

chapters		Downloads
Open access peer-reviewed 1. Reactive Oxygen Species in the Biology of Melanoma By Irene L. Ibañez, Cintia Notcovich, Lucía L. Policastro and Hebe Durán		1511
Open access peer-reviewed 2. The Role of the Microenvironment – Models for the Study of Melanoma By Lucia Speroni, Victoria de los Angeles Bustuoabad, Julieta Gasparri, Nadia Silvia Chiaramoni and Silvia del Valle Alonso		1452
Open access peer-reviewed 3. Circulating Melanoma Cells By Mel Ziman		1776
Open access peer-reviewed 4. Regulation of the Glutathione S-Transferase P1 Expression in Melanoma Cells By Andrii Slonchak, Agata Chwieduk, Joanna Rzeszowska-Wolny and Maria Obolenskaya		1811
Open access peer-reviewed 5. Changing the Nature of Melanoma Cells by Manipulation of Ganglioside Expression By Pu Wang, Sadako Yamagata and Tatsuya Yamagata		1572
Open access peer-reviewed 6. Melanoma Cell Factory for Glycolipid Production By Maria Carmelita Z. Kasuya and Kenichi Hatanaka		1440
Open access peer-reviewed 7. Melanoma-Induced Endothelial Cell Growth Involves Phospholipase A2 and COX2 Upregulation By Mario Alberghina, Carla Motta, Gabriella Lupo, Carmelina D. Anfuso and Renato Bernardini		2296
Open access peer-reviewed 8. Pigment Epithelium-Derived Factor – An Angiostatic Factor with a Broader Function in Melanoma By A. Fernández-Barral, J.L. Orgaz and B. Jiménez		1067
Open access peer-reviewed 9. The Influence of the Skin Microenvironment Air-Liquid Interface on Melanoma By Shuji Toda, Shigehisa Aoki, Kazuyoshi Uchihashi, Aki Matsunobu, Mai Yakushiji, Akifumi Ootani, Eisuke Koike and Nobuhisa Yonemitsu		1149
Open access peer-reviewed 10. Melanocyte Pygmentation – Friend or Foe on the Route to Melanoma By Baldea Ioana		2889
Open access peer-reviewed 11. Melanin and Its Role in Hyper-Pigmentation – Current Knowledge and Future Trends in Research By Manyatja Brenda Mapunya and Namrita Lall		3733
Open access peer-reviewed 12. Genomics of Human Malignant Melanoma By Margit Balázs, Szilvia Ecsedi, Laura Vízkeleti and Ágnes Bégány		1497
Open access peer-reviewed 13. Melanoma and the Nervous System – Novel Pathways Mediated by Neurotrophins and Their Receptors By Carlo Pincelli, Katiuscia Dallaglio and Francesca Truzzi		1624
Open access peer-reviewed 14. The Jak-STAT Signal Transduction Pathway in Melanoma By Courtney Nicholas and Gregory B. Lesinski		2615
Open access peer-reviewed 15. Targeting Adenosine Receptors for the Treatment of Melanoma By Sarvesh Jajoo, Sandeep Sheth, Debashree Mukherjea, Leonard P. Rybak and Vickram Ramkumar		1991
Open access peer-reviewed 16. The Roles of S100 Proteins and RAGE in Melanoma By Estelle Leclerc		2954
Open access peer-reviewed 17. Understanding Melanocyte Transformation – A Work in Progress By Janet Wangari-Talbot, James Goydos and Suzie Chen		1862
Open access peer-reviewed 18. Biomarkers for Melanoma Diagnosis and the Technologies Used to Identify Them By Takeshi Mori and Jeong-Hun Kang		1596
Open access peer-reviewed 19. Characterization of Melanoma Progression on Animal Model Using Fourier Transform Infrared Mapping By Beljebbar A., Gatouillat G., Morjani H., Manfait M. and Madoulet C.		1729
Open access peer-reviewed 20. Ion Channels as Promising Therapeutic Targets for Melanoma By Aurélie Chantôme, Marie Potier-Cartereau, Sébastien Roger, Christophe Vandier, Olivier Soriani and Virginie Joulin		2623
Open access peer-reviewed 21. Targeting the Proteasome in Melanoma By Anabel Sorolla, Andree Yeramian, Xavier Dolcet, Leandro Abal, Eugenia Ortega, Ramon Egido, Xavier Matias-Guiu and Rosa M. Marti		1816
Open access peer-reviewed 22. Nuclear Translocation of YB-1 Protein Induced by Ultraviolet Light and the Investigational Gallium Drug GaQ3 in Melanoma Cells By Seied Mojtaba Valiahdi, Michael A. Jakupec, Sara Daraei, Franz Wohlrab and Bernhard K. Keppler		1593
Open access peer-reviewed 23. Novel Approach to the Characterization of Melanoma Associated-Peptide-Specific CTL Lines from Melanoma Patients By Yasuto Akiyama, Masaru Komiyama, Akira Iizuka, Akifumi Yamamoto, Naoya Yamazaki and Yoshio Kiyohara		1276
Open access peer-reviewed 24. Quantitative Regulation of Melanoma Growth in the Host by Tumor-Specific Serpins in Blood Serum is a Main Reason for Inefficient Tumor Treatment By Donenko F. V., Kiselevskii M.V. and Efferth T.		1645
Open access peer-reviewed 25. Molecular Profiling of A375 Human Malignant Melanoma Cells Treated with Kojic Acid and Arbutin By Jung-Feng Hsieh, Shui-Tein Chen and Sun-Long Cheng		3488
Open access peer-reviewed 26. Anticancer Effects of a Micronutrient Mixture on Melanoma – Modulation of Metastasis and Other Critical Parameters By M.W. Roomi, T. Kalinovsky, A. Niedzwiecki and M. Rath		1529
Open access peer-reviewed 27. RANK/RANKL Axis in Melanoma By Kanji Mori, Kosei Ando, Frédéric Lézot and Dominique Heymann		1179
Open access peer-reviewed 28. Isolation of Cellular Clones of Murine Melanoma Resistants to the Photodynamic Therapy and Characterization of Some Mechanisms Involved in the Radioresistance By Ramón-Gallegos E., Rosas-Flores L., Barrera-Mendoza C.C., Herrera-Carrillo Z., González-Agüero G., Estrada-Manrique G. and Cruz-Orea A.		1604
Open access peer-reviewed 29. Non-Thermal Effects of Near-Infrared Irradiation on Melanoma By Yohei Tanaka and Kiyoshi Matsuo		2867

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