Open access peer-reviewed Edited Volume

Research on Melanoma

A Glimpse into Current Directions and Future Trends

Edited by Mandi Murph

University of Georgia, United States of America

The book Research on Melanoma: A Glimpse into Current Directions and Future Trends, is divided into sections to represent the most cutting-edge topics in melanoma from around the world. The emerging epigenetics of disease, novel therapeutics under development and the molecular signaling aberrations are explained in detail. Since there are a number of areas in which unknowns exist surrounding the complex development of melanoma and its response to therapy, this book illuminates and comprehensively discusses such aspects. It is relevant for teaching the novice researcher who wants to initiate projects in melanoma and the more senior researcher seeking to polish their existing knowledge in this area. Many chapters include visuals and illustrations designed to easily guide the reader through the ideas presented.

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Research on MelanomaA Glimpse into Current Directions and Future TrendsEdited by Mandi Murph

Published: September 12th 2011

DOI: 10.5772/797

ISBN: 978-953-307-293-7

eBook (PDF) ISBN: 978-953-51-6481-4

Copyright year: 2011

Books open for chapter submissions

42764 Total Chapter Downloads

14 Crossref Citations

49 Web of Science Citations

47 Dimensions Citations


Open access peer-reviewed

1. Predictive Capacity and Functional Significance of MicroRNA in Human Melanoma

By Xiaobo Li and Yaguang Xi


Open access peer-reviewed

2. Epigenetic Changes in Melanoma and the Development of Epigenetic Therapy for Melanoma

By Duc P. Do and Syed A.A. Rizvi


Open access peer-reviewed

3. Genetic, Epigenetic and Molecular Changes in Melanoma: A New Paradigm for Biological Classification

By Stefania Staibano, Massimo Mascolo, Maria Siano, Gennaro Ilardi and Gaetano De Rosa


Open access peer-reviewed

4. A Bromophosphonate Analogue of Lysophosphatidic Acid Surpasses Dacarbazine in Reducing Cell Proliferation and Viability of MeWo Melanoma Cells

By Duy Nguyen, Oanh Nguyen, Honglu Zhang, Glenn D. Prestwich and Mandi M. Murph


Open access peer-reviewed

5. Low-Anticoagulant Heparins in the Treatment of Metastasis

By Narayanam V. Rao, Glenn D. Prestwich, John R. Hoidal and Thomas P. Kennedy


Open access peer-reviewed

6. Novel Antifolates as Produgs for the Treatment of Melanoma

By Jose Neptuno Rodriguez-Lopez, Luis Sanchez-del-Campo, Magali Saez-Ayala, Maria F. Montenegro and Juan Cabezas-Herrera


Open access peer-reviewed

7. The Potential of Triterpenoids in the Treatment of Melanoma

By J. Sarek, M. Kvasnica, M. Vlk, M. Urban, P. Dzubak and M. Hajduch


Open access peer-reviewed

8. New Molecular Targets for the Systemic Therapy of Melanoma

By Kausar Begam Riaz Ahmed and Michael A. Davies


Open access peer-reviewed

9. BRAF V600E Mutated Gene Variant as a Circulating Molecular Marker in Metastatic Melanoma Patients

By Viviana Vallacchi, Licia Rivoltini and Monica Rodolfo


Open access peer-reviewed

10. Ultraviolet Light as a Modulator of Melanoma Development

By Graeme Walker and Elke Hacker


Open access peer-reviewed

11. Dual Roles of the Melanoma CAM (MelCAM/METCAM) in Malignant Progression of Melanoma

By Guang-Jer Wu


Open access peer-reviewed

12. Dual Function of Wnts in Human Cutaneous Melanoma

By Ksenia Kulikova, Alexey Kibardin, Nikolay Gnuchev, Georgii Georgiev and Sergey Larin


Open access peer-reviewed

13. A POU3F2-MITF-SHC4 Axis in Phenotype Switching of Melanoma Cells

By Thomas Strub, Dominique Kobi, Dana Koludrovic and Irwin Davidson


Open access peer-reviewed

14. The Role of Cellular Differentiation and Cell Fate in Malignant Melanoma

By Paul Kuzel and Andy J. Chien


Open access peer-reviewed

15. Role of Angiogenesis and Microenvironment in Melanoma Progression

By Roberto Ria, Antonia Reale and Angelo Vacca


Open access peer-reviewed

16. Stromal Microenvironment Alterations in Malignant Melanoma

By Svetlana Brychtova, Michala Bezdekova, Jaroslav Hirnak, Eva Sedlakova, Martin Tichy and Tomas Brychta


Open access peer-reviewed

17. Current Insight Into the Metastatic Process and Melanoma Cell Dissemination

By Isabelle Bourgault-Villada, Michelle Hong, Karen Khoo, Muly Tham, Benjamin Toh,Lu-En Wai and Jean-Pierre Abastado


Open access peer-reviewed

18. Increased Resistance of Vasculogenic Mimicry-Forming Uveal Melanoma Cells against Cytotoxic Agents in Three-Dimensional Cultures

By Klara Valyi-Nagy, Andras Voros, Eva Gagyi and Tibor Valyi-Nagy


Open access peer-reviewed

19. The Role of Adhesion Receptors in Melanoma Metastasis and Therapeutic Intervention Thereof

By Michael Alexander and Gerd Bendas


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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