Open access peer-reviewed Edited Volume

Squamous Cell Carcinoma

This book points to some new areas for investigation on squamous cell carcinoma (SCC). Firstly, the features and management of some specific SCC is discussed to give the readers the general principles in dealing with these uncommon and sophisticated conditions. Some new concepts in adjuvant therapy including neoadjuvant therapy and gold nanoparticle-based photo dynamic therapy are introduced. Secondly, a detailed discussion of molecular aspects of tumor invasion and progression in SCC is provided with the emphasis on the roles of some important factors. The role of tumor microenvironment in head and neck SCC is specifically discussed. Thirdly, the roles of cancer stem cells (CSC) in cancer therapy of SCC are described. Molecular mechanisms involving therapeutic resistance and new therapeutic strategies targeting CSC are discussed in detail. Finally, other aspects concerning SCC are included, which involve the assessment, genetic manipulation and its possible clinical implications for the treatment of SCC.

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Squamous Cell CarcinomaEdited by Xiaoming Li

Published: February 3rd 2012

DOI: 10.5772/1321

ISBN: 978-953-51-0024-9

eBook (PDF) ISBN: 978-953-51-6805-8

Copyright year: 2012

Books open for chapter submissions

72665 Total Chapter Downloads

19 Crossref Citations

18 Web of Science Citations

34 Dimensions Citations


Open access peer-reviewed

1. Metastasis of Head and Neck Squamous Cell Carcinoma

By Xiaoming Li, Yupeng Shen, Bin Di and Qi Song


Open access peer-reviewed

2. Advanced Squamous Cell Carcinoma of the Skin

By Vinicius Vazquez, Sergio Serrano and Renato Capuzzo


Open access peer-reviewed

3. Sarcomatoid Squamous Cell Carcinoma

By Charmaine C. Anderson, Brian H. Le and Bernice Robinson-Bennett


Open access peer-reviewed

4. Basaloid Squamous Cell Carcinoma

By Jasim Radhi


Open access peer-reviewed

5. Neoadjuvant Chemotherapy Using Platinum-Based Regimens for Stage Ib2-II Squamous Cell Carcinoma and Non-Squamous Cell Carcinoma of the Cervix

By Tadahiro Shoji, Eriko Takatori, Hideo Omi, Masahiro Kagabu, Tastuya Honda, Yuichi Morohara, Seisuke Kumagai, Fumiharu Miura, Satoshi Takeuchi, Akira Yoshizaki and Toru Sugiyama


Open access peer-reviewed

6. Combined Therapy For Squamous Carcinoma Cells: Application of Porphyrin-Alkaloid Modified Gold Nanoparticles

By Jarmila Králová, Kamil Záruba, Pavel Řezanka, Pavla Poučková, Lenka Veverková and Vladimír Král


Open access peer-reviewed

7. Cadherin Expression and Progression of Squamous Cell Carcinomas of the Oral Cavity

By Kazushi Imai, Genta Maeda and Tadashige Chiba


Open access peer-reviewed

8. The Role of EphB4 and EphrinB2 in Head and Neck Squamous Cell Carcinoma

By Eric J. Yavrouian, Uttam K. Sinha and Rizwan Masood


Open access peer-reviewed

9. Involvement of Squamous Cell Carcinoma Antigen in Invasion and Metastasis of Squamous Cell Carcinoma of Uterine Cervix

By Akihiro Murakami, Keiko Yoshidomi and Norihiro Sugino


Open access peer-reviewed

10. The Cellular Microenvironment of Head and Neck Squamous Cell Carcinoma

By Maya Mathew and Sufi Mary Thomas


Open access peer-reviewed

11. Role of Connective Tissue Growth Factor (CTGF/CCN2) in Oral Squamous Cell Carcinoma-Induced Bone Destruction

By Tsuyoshi Shimo and Akira Sasaki


Open access peer-reviewed

12. Role of Inflammation in Oral Squamous Cell Carcinoma

By Kıvanç Bektaş-Kayhan


Open access peer-reviewed

13. Molecular Mechanisms Involving Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma (HNSCC) – Roles of Hypoxic Microenvironment and Cancer Stem Cell

By Xiaoming Li, Qingjia Sun and Yupeng Shen


Open access peer-reviewed

14. New Therapeutic Strategies in Small Cell Lung Cancer: The Stem Cell Target

By Guadalupe Aparicio Gallego, Vanessa Medina Villaamil, Guillermo Alonso Curbera and L. Antón Aparicio


Open access peer-reviewed

15. MicroRNA Dysregulation in Squamous Cell Carcinoma of Head and Neck

By Thian-Sze Wong, Wei Gao, Wai-Kuen Ho, Jimmy Yu-Wai Chan, William Ignace Wei and Raymond King-Yin Tsang


Open access peer-reviewed

16. Structural Features, Biological Functions of the Alpha-1 Antitrypsin and Contribution to Esophageal Cancer

By Shahla Mohammad Ganji, Ferdous Rastgar Jazii and Abbas Sahebghadam-Lotfi


Open access peer-reviewed

17. Vitamin D3 and Its Role in the Treatment of Head and Neck Squamous Cell Carcinoma

By M. Rita I. Young and David D. Walker


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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