Open access peer-reviewed Edited Volume

Biological Therapy for Inflammatory Bowel Disease

Edited by Raquel Franco Leal

University of Campinas


Tristan Torriani

University of Campinas

The treatment of inflammatory bowel disease (IBD) has posed a major challenge since its appearance. Biomedical researchers, physicians, gastroenterologists, and surgeons have struggled to improve the quality of life of their patients and have sought, above all else, to keep the disease under remission for as long as possible. Blockers for tumoral necrosis factor alpha (TNF-α) were the first biological drugs to be discovered and for this reason they played a crucial role in the subsequent evolution of IBD treatment. The aim of this book is to provide an overview of such drugs and the latest developments in IBD immunopathology. Our contributors discuss the main indications, efficacy, and possible side effects of the different types of drugs available today for IBD treatment.

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Biological Therapy for Inflammatory Bowel DiseaseEdited by Raquel Franco Leal

Published: March 11th 2020

DOI: 10.5772/intechopen.83074

ISBN: 978-1-83880-264-6

Print ISBN: 978-1-83880-263-9

eBook (PDF) ISBN: 978-1-78985-954-6

Copyright year: 2020

Books open for chapter submissions

4892 Total Chapter Downloads

2 Crossref Citations

3 Dimensions Citations


Open access peer-reviewed

1. Mucosal Immunology in the Inflammatory Bowel Diseases

By Giovanna Rosa Degasperi


Open access peer-reviewed

2. The Role of TNF in the Pathogenesis of Inflammatory Bowel Disease

By Martina Perše and Ana Unkovič


Open access peer-reviewed

3. Traditional Drugs: Mechanisms of Immunosuppressor and Corticosteroid Therapies for Inflammatory Bowel Diseases

By Cristina Ribeiro de Barros Cardoso, Amanda de Castro Habka, Camila Figueiredo Pinzan, Camilla Narjara Simão Oliveira, Jefferson Luiz da Silva and Murillo Duarte-Silva


Open access peer-reviewed

4. Inhibitors of Tumoral Necrosis Factor Alpha in Inflammatory Bowel Disease

By Carlos Walter Sobrado, Natália Sousa Freitas Queiroz and Caio Almeida Perez


Open access peer-reviewed

5. Biological Therapy in the Prevention of Complications of Crohn

By Dolores Ortiz-Masià


Open access peer-reviewed

6. Biological Therapy for Inflammatory Bowel Diseases: Screening Prior to Initiating and How to Proceed When Surgery Is Necessary

By Maria de Lourdes Setsuko Ayrizono, Priscilla de Sene Portel Oliveira and João José Fagundes


Open access peer-reviewed

7. Anti-Integrins, Anti-Interleukin 12/23p40, and JAK Inhibitors for the Inflammatory Bowel Disease Treatment

By Karine Mariane Steigleder, Fernando Lopes Ponte Neto, Cristiane Kibune Nagasako and Raquel Franco Leal


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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