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Ranjith Kumavath

Central University of Kerala India

Dr. Ranjith Kumavath, MSc, PhD, FASB, was born in 1979 to a lovely Rajput Indian couple and grew up in south India. He received his PhD degree from the University of Hyderabad. Before joining CUK in 2011, he worked as a postdoctoral research fellow at the University of Hyderabad, Singapore and the USA. He has been awarded as Young Scientist by DST, Govt. of India; BioAsia Young Scientist by govt. of Andhra Pradesh; Fellow of the Society of Applied Biotechnology by SAB; Fellow of Young Investigator by India Biosciences and Mahatma Gandhi Gold Medal Award 2014; and APJ Abdul Kalam Award by GEPRA, India. Currently, he is operating four major research projects funded by UGC-BSR, SERB-DST and SERB, Govt. of India. He has published 2 books, 6 chapters and 23 research publications in leading international journals, and he has made 18 national and 16 international presentations. He has contributed in discovery of four novel enzymes to IUBMB. He has collaborations with UoH, IIOAB, Cancer Science Institute of Singapore and San Diego State University, USA. His main research interest areas are cancer genomics, microbial genetics and metagenomics, human infective diseases and computational drug designing. His research group is being dedicated towards developing anti-cancer agents from microbial recourses for target-based drug discovery.

2books edited

3chapters authored

Latest work with IntechOpen by Ranjith Kumavath

This book focuses on metagenomics for gut microbiomes. The host is deprived of various benefits derived from the numerous gut microbes for food metabolism and health. However, polysaccharides such as cellulose, xylans, resistant starch, and inulin that are found in vegetables in our diet are digested by certain species that colonize the intestines. In contrast, metagenomic studies that reiterate microbiome intrinsic factors from particular communities and lifestyles and are extremely important for bacterial communities traveling over a long distance have entered a new era. Predominantly to understand the behavior of organisms and their action in a host, next-generation sequencing will provide a new insight into analyzing the livestock industry, agriculture, and human health risks and will consider for future development novel therapies for various diseases through identification of advanced tools. Hence, the book will give more precise information on the role of gut microbiomes in the host.

Metagenomics for Gut Microbes

Metagenomics for Gut Microbes

Edited by Ranjith Kumavath

Books edited

Antibacterial Agents

Antibacterial Agents

Edited by Ranjith Kumavath

Chapters authored

Scientific Swift in Bioremediation: An Overview

By Ranjith N. Kumavath and Pratap Deverapalli

Part of the book: Applied Bioremediation

Metagenomics — A Technological Drift in Bioremediation

By Pratap Devarapalli and Ranjith N. Kumavath

Nature has its ways of resolving imbalances in its environment and microorganisms are one of the best tools of nature to eliminate toxic pollutants. The process of eliminating pollutants using microbes is termed Bioremediation. Metagenomics is a strategic approach for analysing microbial communities at a genomic level. It is one of the best technological upgradation to bioremediation. Identification and screening of metagenomes from the polluted environments are crucial in a metagenomic study. This chapter emphasizes recent multiple case studies explaining the approaches of metagenomics in bioremediation in different contaminated environments such as soil, water etc. The second section explains different sequences and function-based metagenomic strategies and tools starting from providing a detailed view of metagenomic screening, FACS, and multiple advanced metagenomic sequencing strategies dealing with the prevalent metagenomes in bioremediation and giving a list of different widespread metagenomic organisms and their respective projects. Eventually, we have provided a detailed view of different major bioinformatic tools and datasets most prevalently used in metagenomic data analysis and processing during metagenomic bioremediation.

Part of the book: Advances in Bioremediation of Wastewater and Polluted Soil

Metagenomics of Antimicrobial Resistance in Gut Microbiome

By Madangchanok Imchen and Ranjith Kumavath

A healthy human body functions in sync with a wide array of gut microbes collectively known as human gut microbiome. They complement in a number of functions which are essential in our daily life such as in food metabolism. Various illnesses including colon cancer, autism, obesity, and autoimmune diseases have been linked to an imbalanced gut microbiota. Antibiotics are indispensable drug; however, the administration of antibiotics in humans as well as in animal farms has shown to increase antimicrobial resistance genes (ARGs) in gut microbiome. This is of serious concern since the commensals in gut microbiome could capture ARGs through horizontal gene transfer which in turn could cause postsurgical infections. In addition, numerous studies have consistently shown that the gut microbiome is unique to each individual. Hence, in-depth knowledge on the gut microbiota community and the factor responsible for shaping and spreading of ARGs is essential. This would in turn enable the development of custom-tailored personalized food and drugs in the future.

Part of the book: Metagenomics for Gut Microbes

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Vanessa Alves

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Cleide S. T. Araújo

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