Open access peer-reviewed Edited Volume

Colorectal Cancer Biology

From Genes to Tumor

Edited by Rajunor Ettarh

Tulane University, United States of America

Colorectal cancer is a common disease, affecting millions worldwide and represents a global health problem. Effective therapeutic solutions and control measures for the disease will come from the collective research efforts of clinicians and scientists worldwide. This book presents the current status of the strides being made to understand the fundamental scientific basis of colorectal cancer. It provides contributions from scientists, clinicians and investigators from 20 different countries. The four sections of this volume examine the evidence and data in relation to genes and various polymorphisms, tumor microenvironment and infections associated with colorectal cancer. An increasingly better appreciation of the complex inter-connected basic biology of colorectal cancer will translate into effective measures for management and treatment of the disease. Research scientists and investigators as well as clinicians searching for a good understanding of the disease will find this book useful.

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Colorectal Cancer BiologyFrom Genes to TumorEdited by Rajunor Ettarh

Published: February 10th 2012

DOI: 10.5772/1163

ISBN: 978-953-51-0062-1

eBook (PDF) ISBN: 978-953-51-6821-8

Copyright year: 2012

Books open for chapter submissions

46356 Total Chapter Downloads

20 Crossref Citations

33 Web of Science Citations

54 Dimensions Citations


Open access peer-reviewed

1. Colorectal Cancer: It Starts and It Runs

By Rajunor Ettarh


Open access peer-reviewed

2. Germline Genetics in Colorectal Cancer Susceptibility and Prognosis

By Amanda Ewart Toland


Open access peer-reviewed

3. The Role of Modifier Genes in Lynch Syndrome

By Rodney J. Scott, Stuart Reeves and Bente Talseth-Palmer


Open access peer-reviewed

4. Cytokine Gene Polymorphisms in Colorectal Cancer

By Spaska Stanilova


Open access peer-reviewed

5. Glutathione-S-Transferases in Development, Progression and Therapy of Colorectal Cancer

By Tatyana Vlaykova, Maya Gulubova, Yovcho Yovchev, Dimo Dimov, Denitsa Vlaykova Petjo Chilingirov and Nikolai Zhelev


Open access peer-reviewed

6. Distinct Pathologic Roles for Glycogen Synthase Kinase 3β in Colorectal Cancer Progression

By Toshinari Minamoto, Masanori Kotake Mitsutoshi Nakada, Takeo Shimasaki, Yoshiharu Motoo and Kazuyuki Kawakami


Open access peer-reviewed

7. Molecular Traits of the Budding Colorectal Cancer Cells

By Boye Schnack Nielsen


Open access peer-reviewed

8. Lipid Peroxidation in Colorectal Carcinogenesis: Bad and Good News

By Stefania Pizzimenti, Cristina Toaldo, Piergiorgio Pettazzoni, Eric Ciamporcero, Mario Umberto Dianzani and Giuseppina Barrera


Open access peer-reviewed

9. Growth Factors and the Redox State as New Therapeutic Targets for Colorectal Cancer

By Teodoro Palomares, Marta Caramés, Ignacio García-Alonso and Ana Alonso-Varona


Open access peer-reviewed

10. Human Tip60 (NuA4) Complex and Cancer

By Hiroshi Y. Yamada


Open access peer-reviewed

11. Characterization of the Cell Membrane During Cancer Transformation

By Barbara Szachowicz-Petelska, Izabela Dobrzyńska, Stanisław Sulkowski and Zbigniew A. Figaszewski


Open access peer-reviewed

12. Emergent Concepts from the Intestinal Guanylyl Cyclase C Pathway

By Mehboob Ali and Giovanni M. Pitari


Open access peer-reviewed

13. Molecular Mechanisms of Lymphatic Metastasis

By M.C. Langheinrich, V. Schellerer, K. Oeckl, M. Stürzl, E. Naschberger and R.S. Croner


Open access peer-reviewed

14. Modulation of Tumor Angiogenesis by a Host Anti-Tumor Response in Colorectal Cancer

By N. Britzen-Laurent, V.S. Schellerer, R.S. Croner M. Stürzl1 and E. Naschberger


Open access peer-reviewed

15. Adaptive and Innate Immunity, Non Clonal Players in Colorectal Cancer Progression

By Lucia Fini, Fabio Grizzi and Luigi Laghi


Open access peer-reviewed

16. The Role of Infectious Agents in Colorectal Carcinogenesis

By Hytham K.S. Hamid and Yassin M. Mustafa


Open access peer-reviewed

17. Streptococcus bovis/gallolyticus Induce the Development of Colorectal Cancer

By A.S. Abdulamir, R.R. Hafidh and F. Abu Bakar


Open access peer-reviewed

18. Intestinal Host-Microbiome Interactions

By Harold Tjalsma and Annemarie Boleij


Open access peer-reviewed

19. Tumor Infiltrating Lymphocytes as Prognostic Factor of Early Recurrence and Poor Prognosis of Colorectal Cancer After Radical Surgical Treatment

By Vaclav Liska, Ondrej Daum, Petr Novak, Vladislav Treska, Ondrej Vycital, Jan Bruha, Pavel Pitule and Lubos Holubec


Open access peer-reviewed

20. Fluorescent Biomarker in Colorectal Cancer

By E. Kirilova, I. Kalnina, G. Kirilov and G. Gorbenko


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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