Open access peer-reviewed Edited Volume

Oncogene and Cancer

From Bench to Clinic

Edited by Yahwardiah Siregar

University of North Sumatra, Indonesia

This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors

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Oncogene and CancerFrom Bench to ClinicEdited by Yahwardiah Siregar

Published: January 24th 2013

DOI: 10.5772/3217

ISBN: 978-953-51-0858-0

eBook (PDF) ISBN: 978-953-51-7071-6

Copyright year: 2013

Books open for chapter submissions

49398 Total Chapter Downloads

26 Crossref Citations

32 Web of Science Citations

55 Dimensions Citations


Open access peer-reviewed

1. Serial Changes in Expression of Proteins in Response to Neoadjuvant Chemotherapy in Breast Cancer

By Daniel Chan and Soo-Chin Lee


Open access peer-reviewed

2. HER2-Driven Carcinogenesis: New Mouse Models for Novel Immunotherapies

By Cristina Marchini, Lucia Pietrella, Cristina Kalogris, Chiara Garulli, Federico Gabrielli, Elena Quaglino, Manuela Iezzi, Serenella M. Pupa, Elda Tagliabue and Augusto Amici


Open access peer-reviewed

3. HER2 Amplification or Overexpression in Upper GI Tract and Breast Cancer with Clinical Diagnosis and Treatment

By Zhongren Zhou and David G. Hick


Open access peer-reviewed

4. Emerging Roles of Atypical Dual Specificity Phosphatases in Cancer

By Erica L. Cain and Alexander Beeser


Open access peer-reviewed

5. DNA Repair Molecules and Cancer Therapeutical Responses

By Yasuko Kitagishi, Mayumi Kobayashi and Satoru Matsuda


Open access peer-reviewed

6. Structure-Based Approaches Targeting Oncogene Promoter G-Quadruplexes

By Dik-Lung Ma, Victor Pui-Yan Ma, Ka-Ho Leung, Hai-Jing Zhong, Hong-Zhang He, Daniel Shiu-Hin Chan and Chung-Hang Leung


Open access peer-reviewed

7. Cancer Genes and Chromosome Instability

By Alexey Stepanenko and Vadym Kavsan


Open access peer-reviewed

8. Human Papillomaviruses Oncoproteins

By Gabriela Anton, Adriana Plesa, Coralia Bleotu, Anca Botezatu, Mariana Anton, Lorelei Irina Brasoveanu and Mihai Stoian


Open access peer-reviewed

9. Model Systems Facilitating an Understanding of Mechanisms for Oncogene Amplification

By Takaaki Watanabe


Open access peer-reviewed

10. MLL Gene Alterations in Acute Myeloid Leukaemia (11q23/MLL+ AML)

By Denisa Ilencikova and Alexandra Kolenova


Open access peer-reviewed

11. Dual Role of TLR3 in Inflammation and Cancer Cell Apoptosis

By Yann Estornes, Olivier Micheau, Toufic Renno and Serge Lebecque


Open access peer-reviewed

12. A Different Approach for Cellular Oncogene Identification Came from Drosophila Genetics

By Laura Monica Magdalena and Lorand Savu


Open access peer-reviewed

13. Post-Transcriptional Regulation of Proto-Oncogene c-fms in Breast Cancer

By Ho-Hyung Woo and Setsuko K. Chambers


Open access peer-reviewed

14. Non-Coding RNAs and Cancer

By Gianpiero Di Leva and Michela Garofalo


Open access peer-reviewed

15. MiRNA and Proline Metabolism in Cancer

By Wei Liu and James M. Phang


Open access peer-reviewed

16. microRNA: New Players in Metastatic Process

By Tiziana Triulzi, Marilena V. Iorio, Elda Tagliabue and Patrizia Casalini


Open access peer-reviewed

17. Is CCDC26 a Novel Cancer-Associated Long-Chain Non-Coding RNA?

By Tetsuo Hirano


Open access peer-reviewed

18. The MYCN Oncogene

By Leanna Cheung, Jayne E. Murray, Michelle Haber and Murray D. Norris


Open access peer-reviewed

19. STAT Transcription Factors in Tumor Development and Targeted Therapy of Malignancies

By Gordana Konjević, Sandra Radenković, Ana Vuletić, Katarina Mirjačić Martinović, Vladimir Jurišić and Tatjana Srdic


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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