Open access peer-reviewed Edited Volume

Breast Cancer

Carcinogenesis, Cell Growth and Signalling Pathways


Esra Gunduz

Fatih University, Turkey

Cancer is the leading cause of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females. In this book, we discussed various aspects of breast cancer carcinogenesis from clinics to its hormone-based as well as genetic-based etiologies for this deadly cancer. We hope that this book will contribute to the development of novel diagnostic as well as therapeutic approaches.

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Breast CancerCarcinogenesis, Cell Growth and Signalling PathwaysEdited by Mehmet Gunduz

Published: November 30th 2011

DOI: 10.5772/855

ISBN: 978-953-307-714-7

eBook (PDF) ISBN: 978-953-51-6592-7

Copyright year: 2011

Books open for chapter submissions

89520 Total Chapter Downloads

14 Crossref Citations

67 Web of Science Citations

67 Dimensions Citations


Open access peer-reviewed

1. EGFR-Ligand Signaling in Breast Cancer Metastasis: Recurring Developmental Themes

By Nicole K. Nickerson, Jennifer L. Gilmore, Kah Tan Allen, David J. Riese II, Kenneth P. Nephew and John Foley


Open access peer-reviewed

2. EGF Regulation of HRPAP20: A Role for Calmodulin and Protein Kinase C in Breast Cancer Cells

By Manasi N. Shukla, Donna J. Buckley and Arthur R. Buckley


Open access peer-reviewed

3. Endocytic Trafficking of the Epidermal Growth Factor Receptor in Transformed Cells

By Brian P. Ceresa


Open access peer-reviewed

4. HER-2 Signaling in Human Breast Cancer

By Kathleen M. Woods Ignatoski


Open access peer-reviewed

5. Brain Metastases Progression of Breast Cancer

By Ala-Eddin Al Moustafa, Amber Yasmeen, Lina Ghabreau, Ali H. Mohamed and Amal Achkhar


Open access peer-reviewed

6. Signal Transduction Pathways in Breast Cancer – Drug Targets and Challenges

By Samar Azab and Ayman Al-Hendy


Open access peer-reviewed

7. ErbB2/HER2: Its Contribution to Basic Cancer Biology and the Development of Molecular Targeted Therapy

By Tadashi Yamamoto, Makoto Saito, Kentaro Kumazawa, Ayano Doi, Atsuka Matsui, Shiori Takebe, Takuya Amari, Masaaki Oyama and Kentaro Semba


Open access peer-reviewed

8. Trastuzumab-Resistance and Breast Cancer

By Milos Dokmanovic and Wen Jin Wu


Open access peer-reviewed

9. Targeting HER-2 Signaling Network: Implication in Radiation Response

By In Ah Kim


Open access peer-reviewed

10. The Importance of ERα/ERβ Ratio in Breast Cancer: Mitochondrial Function and Oxidative Stress

By Pilar Roca, Jordi Oliver, Jorge Sastre-Serra and Mercedes Nadal-Serrano


Open access peer-reviewed

11. Heterogeneity of Phenotype in Breast Cancer Cell Lines

By Bruce C. Baguley and Euphemia Leung


Open access peer-reviewed

12. Metabolomics and Transcriptional Responses in Estrogen Receptor Positive Breast Cancer Cells

By Soma Mandal, Protiti Khan, Lin Li and James R. Davie


Open access peer-reviewed

13. ER-Alpha36 Mediates Non-Genomic Estrogen and Anti-Estrogen Signaling in Breast Cancer Cells

By ZhaoYi Wang, XianTian Zhang and LianGuo Kang


Open access peer-reviewed

14. Estrogen-Related Receptors and Breast Cancer: A Mini Review

By Christina T. Teng and Peggy R. Teng


Open access peer-reviewed

15. The Role of MicroRNAs in Estrogen Receptor α-Positive Human Breast Cancer

By Hiroko Yamashita, Tatsuya Toyama, Nobuyasu Yoshimoto, Yumi Endo, Mai Iwasa and Yoshitaka Fujii


Open access peer-reviewed

16. Roles of SWI/SNF Complex Genes in Breast Cancer

By Esra Gunduz, Mehmet Gunduz, Bunyamin Isik and Omer Faruk Hatipoglu


Open access peer-reviewed

17. p53, p63 and p73 Network in Breast Cancers

By Chee-Onn Leong


Open access peer-reviewed

18. Role of ING Family Tumor Suppressors in Breast Cancer

By Mehmet Gunduz, Esra Gunduz, Mikdat Bozer and Ramazan Yigitoglu


Open access peer-reviewed

19. Lipid Rafts as Master Regulators of Breast Cancer Cell Function

By Irina S. Babina, Simona Donatello, Ivan R. Nabi and Ann M. Hopkins


Open access peer-reviewed

20. Differences in Membrane Composition and Organization of Crucial Molecules Define the Invasive Properties of MCF-7 Breast Cancer Cells

By Van slambrouck Séverine and Steelant Wim


Open access peer-reviewed

21. Adipose Tissue and Desmoplastic Response in Breast Cancer

By Jorge Martinez and Mariana Cifuentes


Open access peer-reviewed

22. Cross-Talk of Breast Cancer Cells with the Immune System

By Sandra Demaria, Karsten A. Pilones and Sylvia Adams


Open access peer-reviewed

23. Engineering Transcription Factors in Breast Cancer Stem Cells

By Pilar Blancafort, Karla Oyuky Juarez, Sabine Stolzenburg and Adriana S. Beltran


Open access peer-reviewed

24. Breast Cancer Stem Cells – A Review

By Julia S. Samaddar and Edmond Ritter


Open access peer-reviewed

25. Potential Roles of miR-106a in Breast Cancer

By KuanHui E. Chen and Ameae M. Walker


Open access peer-reviewed

26. Scleroderma and Breast Cancer

By Adamantios Michalinos, Michalis Kontos and Ian S. Fentiman


Open access peer-reviewed

27. FZD7 in Triple Negative Breast Cancer Cells

By Lixin Yang, Charles C.H. Kim and Yun Yen


Open access peer-reviewed

28. Dysregulation of Wnt Signaling in Breast Cancer

By Taj D. King and Yonghe Li


Open access peer-reviewed

29. Interactions of STAP-2 with BRK and STAT3/5 in Breast Cancer Cells

By Osamu Ikeda, Yuichi Sekine and Tadashi Matsuda


Open access peer-reviewed

30. Histamine and Breast Cancer: A New Role for a Well Known Amine

By Graciela Cricco, Nora Mohamad, María Soledad Sáez, Eduardo Valli, Elena Rivera and Gabriela Martín


Open access peer-reviewed

31. 1,25(OH)2D3 and Cyclooxygenase-2: Possible Targets for Breast Cancer?

By M. Thill, S. Becker, D. Fischer, K. Diedrich, D. Salehin and M. Friedrich


Open access peer-reviewed

32. Calcium, Ca2+-Sensing Receptor and Breast Cancer

By Chunfa Huang and R. Tyler Miller


Open access peer-reviewed

33. Signal Transduction Pathways Mediated by Unsaturated Free Fatty Acids in Breast Cancer Cells

By Eduardo Perez Salazar, Luis Castro-Sanchez and Pedro Cortes-Reynosa


Open access peer-reviewed

34. Adrenoceptors and Breast Cancer: Review Article

By Roisman Reuth, Alex Beny, Reznick Abraham Zeev, Klemm Ofer, Raphaeli Guy and Roisman Isaac


Open access peer-reviewed

35. Steroid Receptor Coactivators and Their Expression, Regulation and Functional Role in Endocrine Responsive and Resistant Breast Cancer

By Line L. Haugan Moi, Marianne Hauglid Flågeng, Ingvild S. Fenne, Jennifer Gjerde, Ernst A. Lien and Gunnar Mellgren


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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